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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRSS22
All Species:
13.33
Human Site:
T194
Identified Species:
41.9
UniProt:
Q9GZN4
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9GZN4
NP_071402.1
317
33732
T194
V
P
L
P
H
P
Q
T
L
Q
K
L
K
V
P
Chimpanzee
Pan troglodytes
XP_510756
634
67040
T511
V
P
L
P
H
P
Q
T
L
Q
K
L
K
V
P
Rhesus Macaque
Macaca mulatta
XP_001086389
323
35273
L181
N
P
R
I
L
Q
K
L
A
V
P
I
I
D
T
Dog
Lupus familis
XP_547176
308
33063
T193
V
P
L
A
H
P
Q
T
L
Q
K
L
E
V
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9ER10
306
33244
T194
V
P
L
P
H
P
Q
T
L
Q
K
L
K
V
P
Rat
Rattus norvegicus
Q6BEA2
328
35785
I180
D
R
L
P
N
P
R
I
L
Q
K
L
A
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514436
385
42176
L178
P
L
P
P
P
K
K
L
Q
K
L
E
V
P
I
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001081364
389
42357
Q199
I
P
D
F
S
F
I
Q
E
D
M
V
C
A
G
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.3
46.1
75.3
N.A.
74.4
44.5
N.A.
51.4
N.A.
36.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
49.6
61.6
84.8
N.A.
82.3
60.9
N.A.
62
N.A.
48
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
86.6
N.A.
100
60
N.A.
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
93.3
N.A.
100
73.3
N.A.
20
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
13
0
0
0
0
13
0
0
0
13
13
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% C
% Asp:
13
0
13
0
0
0
0
0
0
13
0
0
0
13
0
% D
% Glu:
0
0
0
0
0
0
0
0
13
0
0
13
13
0
0
% E
% Phe:
0
0
0
13
0
13
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% G
% His:
0
0
0
0
50
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
13
0
0
13
0
0
13
13
0
0
0
13
13
0
13
% I
% Lys:
0
0
0
0
0
13
25
0
0
13
63
0
38
0
0
% K
% Leu:
0
13
63
0
13
0
0
25
63
0
13
63
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% M
% Asn:
13
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
13
75
13
63
13
63
0
0
0
0
13
0
0
13
63
% P
% Gln:
0
0
0
0
0
13
50
13
13
63
0
0
0
0
0
% Q
% Arg:
0
13
13
0
0
0
13
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
50
0
0
0
0
0
0
13
% T
% Val:
50
0
0
0
0
0
0
0
0
13
0
13
13
63
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _