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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DERL2 All Species: 48.48
Human Site: S89 Identified Species: 76.19
UniProt: Q9GZP9 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZP9 NP_057125.2 239 27567 S89 C R M L E E G S F R G R T A D
Chimpanzee Pan troglodytes XP_001166612 240 27760 S89 C R M L E E G S F R G R T A D
Rhesus Macaque Macaca mulatta XP_001085558 235 26695 S89 C R M L E E G S F R G R T A D
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8BNI4 239 27621 S89 C R M L E E G S F R G R T A D
Rat Rattus norvegicus XP_001079920 239 27621 S89 C R M L E E G S F R G R T A D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507159 211 24620 L87 F L M T L F G L L A S L F F L
Chicken Gallus gallus XP_415746 239 27598 S89 C R M L E E G S F R G R T A D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001019566 239 27580 S89 C R M L E E G S F R G R T A D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VQ57 245 28238 Q89 S S K L E K D Q Y S R S P A D
Honey Bee Apis mellifera XP_397412 238 27920 S89 C R M L E E G S F R R R T A D
Nematode Worm Caenorhab. elegans Q21997 237 28015 S87 C M M L E E G S F R G R R A D
Sea Urchin Strong. purpuratus XP_786599 252 29483 S89 C R M L E E G S F R G R T A D
Poplar Tree Populus trichocarpa
Maize Zea mays Q4G2J4 249 28488 S88 C K L L E E N S F R G R T A D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZS88 244 28080 S88 C K L L E E N S F R G K T A D
Baker's Yeast Sacchar. cerevisiae Q12743 341 38112 A137 C I L A I T T A T T I I Y G S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.4 73.2 N.A. N.A. 98.7 97.9 N.A. 73.2 93.3 N.A. 88.6 N.A. 28.5 70.2 64 70.6
Protein Similarity: 100 95.8 83.2 N.A. N.A. 99.5 99.1 N.A. 79.9 98.3 N.A. 95.8 N.A. 48.9 83.2 74.4 83.3
P-Site Identity: 100 100 100 N.A. N.A. 100 100 N.A. 13.3 100 N.A. 100 N.A. 26.6 93.3 86.6 100
P-Site Similarity: 100 100 100 N.A. N.A. 100 100 N.A. 13.3 100 N.A. 100 N.A. 40 93.3 86.6 100
Percent
Protein Identity: N.A. 46.9 N.A. 47.9 22.5 N.A.
Protein Similarity: N.A. 65.8 N.A. 66.8 35.1 N.A.
P-Site Identity: N.A. 80 N.A. 73.3 6.6 N.A.
P-Site Similarity: N.A. 93.3 N.A. 93.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 0 0 0 7 0 7 0 0 0 87 0 % A
% Cys: 87 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 87 % D
% Glu: 0 0 0 0 87 80 0 0 0 0 0 0 0 0 0 % E
% Phe: 7 0 0 0 0 7 0 0 80 0 0 0 7 7 0 % F
% Gly: 0 0 0 0 0 0 74 0 0 0 74 0 0 7 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 0 7 0 0 0 0 0 7 7 0 0 0 % I
% Lys: 0 14 7 0 0 7 0 0 0 0 0 7 0 0 0 % K
% Leu: 0 7 20 87 7 0 0 7 7 0 0 7 0 0 7 % L
% Met: 0 7 74 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 14 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % P
% Gln: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % Q
% Arg: 0 60 0 0 0 0 0 0 0 80 14 74 7 0 0 % R
% Ser: 7 7 0 0 0 0 0 80 0 7 7 7 0 0 7 % S
% Thr: 0 0 0 7 0 7 7 0 7 7 0 0 74 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 7 0 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _