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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DERL2 All Species: 26.97
Human Site: T211 Identified Species: 42.38
UniProt: Q9GZP9 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.36
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZP9 NP_057125.2 239 27567 T211 I L K A I F D T P D E D P N Y
Chimpanzee Pan troglodytes XP_001166612 240 27760 T212 I L K A I F D T P D E D P N Y
Rhesus Macaque Macaca mulatta XP_001085558 235 26695 A211 F L K L L L D A P A E D P N Y
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8BNI4 239 27621 T211 I L R T I F D T P D E D P N Y
Rat Rattus norvegicus XP_001079920 239 27621 T211 I L R T I F D T P D E D P N Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507159 211 24620 E197 P N Y N P L P E D G P E P G P
Chicken Gallus gallus XP_415746 239 27598 T211 V L K A I F D T P E D D P N Y
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001019566 239 27580 T211 I L K M L F D T P E E D A N Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VQ57 245 28238 D210 F L K R L V P D V S G G F G G
Honey Bee Apis mellifera XP_397412 238 27920 A211 I L K T L F D A H P E D P D Y
Nematode Worm Caenorhab. elegans Q21997 237 28015 E209 W L V Y L F D E R R P E P L P
Sea Urchin Strong. purpuratus XP_786599 252 29483 T211 I L K T L L D T A P E D P N Y
Poplar Tree Populus trichocarpa
Maize Zea mays Q4G2J4 249 28488 D220 F I K A L F A D D N V V V A Q
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZS88 244 28080 D220 F L K A L F A D E P V V V A R
Baker's Yeast Sacchar. cerevisiae Q12743 341 38112 T264 I T G A H N E T A T F N N N F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.4 73.2 N.A. N.A. 98.7 97.9 N.A. 73.2 93.3 N.A. 88.6 N.A. 28.5 70.2 64 70.6
Protein Similarity: 100 95.8 83.2 N.A. N.A. 99.5 99.1 N.A. 79.9 98.3 N.A. 95.8 N.A. 48.9 83.2 74.4 83.3
P-Site Identity: 100 100 60 N.A. N.A. 86.6 86.6 N.A. 6.6 80 N.A. 73.3 N.A. 13.3 60 26.6 66.6
P-Site Similarity: 100 100 66.6 N.A. N.A. 93.3 93.3 N.A. 13.3 100 N.A. 86.6 N.A. 20 73.3 40 73.3
Percent
Protein Identity: N.A. 46.9 N.A. 47.9 22.5 N.A.
Protein Similarity: N.A. 65.8 N.A. 66.8 35.1 N.A.
P-Site Identity: N.A. 20 N.A. 26.6 26.6 N.A.
P-Site Similarity: N.A. 40 N.A. 33.3 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 40 0 0 14 14 14 7 0 0 7 14 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 67 20 14 27 7 60 0 7 0 % D
% Glu: 0 0 0 0 0 0 7 14 7 14 54 14 0 0 0 % E
% Phe: 27 0 0 0 0 67 0 0 0 0 7 0 7 0 7 % F
% Gly: 0 0 7 0 0 0 0 0 0 7 7 7 0 14 7 % G
% His: 0 0 0 0 7 0 0 0 7 0 0 0 0 0 0 % H
% Ile: 54 7 0 0 34 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 67 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 80 0 7 54 20 0 0 0 0 0 0 0 7 0 % L
% Met: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 0 7 0 7 0 0 0 7 0 7 7 60 0 % N
% Pro: 7 0 0 0 7 0 14 0 47 20 14 0 67 0 14 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % Q
% Arg: 0 0 14 7 0 0 0 0 7 7 0 0 0 0 7 % R
% Ser: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % S
% Thr: 0 7 0 27 0 0 0 54 0 7 0 0 0 0 0 % T
% Val: 7 0 7 0 0 7 0 0 7 0 14 14 14 0 0 % V
% Trp: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 7 0 0 0 0 0 0 0 0 0 0 60 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _