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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DERL2 All Species: 19.09
Human Site: Y138 Identified Species: 30
UniProt: Q9GZP9 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZP9 NP_057125.2 239 27567 Y138 V W S R R N P Y V R M N F F G
Chimpanzee Pan troglodytes XP_001166612 240 27760 P138 Y V W S R R N P Y V R M N F F
Rhesus Macaque Macaca mulatta XP_001085558 235 26695 R138 V W S R R S P R V R V N F F G
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8BNI4 239 27621 Y138 V W S R R N P Y V R M N F F G
Rat Rattus norvegicus XP_001079920 239 27621 Y138 V W S R R N P Y V R M N F F G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507159 211 24620 S136 P W V L M G F S L L L G N S I
Chicken Gallus gallus XP_415746 239 27598 Y138 V W S R R N P Y V R M N F F G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001019566 239 27580 N138 I W S R R N P N V R M N F F G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VQ57 245 28238 D138 I W C Q L N K D V T V S F W F
Honey Bee Apis mellifera XP_397412 238 27920 F138 V W S R R N P F V R L N F F G
Nematode Worm Caenorhab. elegans Q21997 237 28015 M136 I W S R R N P M I Q M N F F G
Sea Urchin Strong. purpuratus XP_786599 252 29483 Y138 V W S R R N P Y I R M N F F G
Poplar Tree Populus trichocarpa
Maize Zea mays Q4G2J4 249 28488 M137 L S N S L T F M M V Y V W S K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZS88 244 28080 M137 L S N S L T F M M V Y V W S K
Baker's Yeast Sacchar. cerevisiae Q12743 341 38112 L186 V W G K Y F P L I Q L F I S F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.4 73.2 N.A. N.A. 98.7 97.9 N.A. 73.2 93.3 N.A. 88.6 N.A. 28.5 70.2 64 70.6
Protein Similarity: 100 95.8 83.2 N.A. N.A. 99.5 99.1 N.A. 79.9 98.3 N.A. 95.8 N.A. 48.9 83.2 74.4 83.3
P-Site Identity: 100 13.3 80 N.A. N.A. 100 100 N.A. 6.6 100 N.A. 86.6 N.A. 26.6 86.6 73.3 93.3
P-Site Similarity: 100 13.3 93.3 N.A. N.A. 100 100 N.A. 20 100 N.A. 93.3 N.A. 60 100 93.3 100
Percent
Protein Identity: N.A. 46.9 N.A. 47.9 22.5 N.A.
Protein Similarity: N.A. 65.8 N.A. 66.8 35.1 N.A.
P-Site Identity: N.A. 0 N.A. 0 20 N.A.
P-Site Similarity: N.A. 26.6 N.A. 26.6 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 7 20 7 0 0 0 7 67 67 20 % F
% Gly: 0 0 7 0 0 7 0 0 0 0 0 7 0 0 60 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 20 0 0 0 0 0 0 0 20 0 0 0 7 0 7 % I
% Lys: 0 0 0 7 0 0 7 0 0 0 0 0 0 0 14 % K
% Leu: 14 0 0 7 20 0 0 7 7 7 20 0 0 0 0 % L
% Met: 0 0 0 0 7 0 0 20 14 0 47 7 0 0 0 % M
% Asn: 0 0 14 0 0 60 7 7 0 0 0 60 14 0 0 % N
% Pro: 7 0 0 0 0 0 67 7 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 7 0 0 0 0 0 14 0 0 0 0 0 % Q
% Arg: 0 0 0 60 67 7 0 7 0 54 7 0 0 0 0 % R
% Ser: 0 14 60 20 0 7 0 7 0 0 0 7 0 27 0 % S
% Thr: 0 0 0 0 0 14 0 0 0 7 0 0 0 0 0 % T
% Val: 54 7 7 0 0 0 0 0 54 20 14 14 0 0 0 % V
% Trp: 0 80 7 0 0 0 0 0 0 0 0 0 14 7 0 % W
% Tyr: 7 0 0 0 7 0 0 34 7 0 14 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _