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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DERL2
All Species:
32.73
Human Site:
Y218
Identified Species:
51.43
UniProt:
Q9GZP9
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9GZP9
NP_057125.2
239
27567
Y218
T
P
D
E
D
P
N
Y
N
P
L
P
E
E
R
Chimpanzee
Pan troglodytes
XP_001166612
240
27760
Y219
T
P
D
E
D
P
N
Y
N
P
L
P
E
E
R
Rhesus Macaque
Macaca mulatta
XP_001085558
235
26695
Y218
A
P
A
E
D
P
N
Y
L
P
L
P
E
E
Q
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8BNI4
239
27621
Y218
T
P
D
E
D
P
N
Y
N
P
L
P
E
E
R
Rat
Rattus norvegicus
XP_001079920
239
27621
Y218
T
P
D
E
D
P
N
Y
N
P
L
P
E
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507159
211
24620
P204
E
D
G
P
E
P
G
P
A
Q
R
P
P
R
Q
Chicken
Gallus gallus
XP_415746
239
27598
Y218
T
P
E
D
D
P
N
Y
N
P
L
P
E
E
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001019566
239
27580
Y218
T
P
E
E
D
A
N
Y
N
P
L
P
E
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQ57
245
28238
G217
D
V
S
G
G
F
G
G
F
G
L
P
P
E
S
Honey Bee
Apis mellifera
XP_397412
238
27920
Y218
A
H
P
E
D
P
D
Y
T
P
P
P
E
D
R
Nematode Worm
Caenorhab. elegans
Q21997
237
28015
P216
E
R
R
P
E
P
L
P
E
D
E
R
P
G
G
Sea Urchin
Strong. purpuratus
XP_786599
252
29483
Y218
T
A
P
E
D
P
N
Y
N
P
L
P
E
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q4G2J4
249
28488
Q227
D
D
N
V
V
V
A
Q
P
P
N
A
G
I
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZS88
244
28080
R227
D
E
P
V
V
V
A
R
P
E
D
V
R
F
A
Baker's Yeast
Sacchar. cerevisiae
Q12743
341
38112
F271
T
A
T
F
N
N
N
F
A
N
V
P
S
S
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.4
73.2
N.A.
N.A.
98.7
97.9
N.A.
73.2
93.3
N.A.
88.6
N.A.
28.5
70.2
64
70.6
Protein Similarity:
100
95.8
83.2
N.A.
N.A.
99.5
99.1
N.A.
79.9
98.3
N.A.
95.8
N.A.
48.9
83.2
74.4
83.3
P-Site Identity:
100
100
73.3
N.A.
N.A.
100
100
N.A.
13.3
86.6
N.A.
80
N.A.
20
53.3
6.6
80
P-Site Similarity:
100
100
80
N.A.
N.A.
100
100
N.A.
26.6
100
N.A.
93.3
N.A.
20
66.6
13.3
80
Percent
Protein Identity:
N.A.
46.9
N.A.
47.9
22.5
N.A.
Protein Similarity:
N.A.
65.8
N.A.
66.8
35.1
N.A.
P-Site Identity:
N.A.
6.6
N.A.
0
20
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
0
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
14
7
0
0
7
14
0
14
0
0
7
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
14
27
7
60
0
7
0
0
7
7
0
0
14
0
% D
% Glu:
14
7
14
54
14
0
0
0
7
7
7
0
60
54
7
% E
% Phe:
0
0
0
7
0
7
0
7
7
0
0
0
0
7
0
% F
% Gly:
0
0
7
7
7
0
14
7
0
7
0
0
7
7
14
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
7
0
7
0
60
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
7
7
60
0
47
7
7
0
0
0
0
% N
% Pro:
0
47
20
14
0
67
0
14
14
67
7
80
20
0
0
% P
% Gln:
0
0
0
0
0
0
0
7
0
7
0
0
0
0
20
% Q
% Arg:
0
7
7
0
0
0
0
7
0
0
7
7
7
7
47
% R
% Ser:
0
0
7
0
0
0
0
0
0
0
0
0
7
7
7
% S
% Thr:
54
0
7
0
0
0
0
0
7
0
0
0
0
0
0
% T
% Val:
0
7
0
14
14
14
0
0
0
0
7
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
60
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _