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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COMMD5
All Species:
10.3
Human Site:
T108
Identified Species:
20.61
UniProt:
Q9GZQ3
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9GZQ3
NP_001074472.1
224
24670
T108
P
T
S
L
K
P
D
T
F
R
D
Q
L
Q
E
Chimpanzee
Pan troglodytes
XP_520030
224
24631
S108
P
T
S
L
K
P
D
S
F
R
D
Q
L
Q
E
Rhesus Macaque
Macaca mulatta
XP_001095693
224
24732
T108
P
A
S
L
K
P
D
T
F
R
D
Q
L
Q
E
Dog
Lupus familis
XP_539226
378
40596
A262
A
A
S
L
K
P
D
A
F
K
D
Q
L
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8R395
224
24475
A108
P
A
S
L
K
P
D
A
F
Q
D
E
L
Q
E
Rat
Rattus norvegicus
Q9ERR2
224
24435
A108
P
A
S
L
K
P
D
A
F
Q
E
E
L
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517801
72
8052
Chicken
Gallus gallus
NP_001008465
226
24886
V110
L
S
T
F
K
Q
E
V
F
K
E
D
L
K
E
Frog
Xenopus laevis
NP_001087091
224
25501
V108
V
S
T
L
K
Q
E
V
F
K
E
D
L
K
E
Zebra Danio
Brachydanio rerio
NP_001003553
205
22909
E101
L
R
A
L
R
I
S
E
E
L
L
A
D
I
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121988
201
23447
S98
P
E
C
I
D
D
L
S
I
V
V
Y
G
Q
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792838
220
24374
L104
Q
T
S
L
K
Q
E
L
F
K
A
D
L
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
96.4
50.5
N.A.
79
80.3
N.A.
23.6
53.9
52.6
43.7
N.A.
N.A.
25.8
N.A.
42.8
Protein Similarity:
100
99.1
97.3
54.2
N.A.
88.8
90.1
N.A.
29.4
76.5
76.3
66.9
N.A.
N.A.
50
N.A.
62.9
P-Site Identity:
100
93.3
93.3
73.3
N.A.
73.3
66.6
N.A.
0
26.6
33.3
6.6
N.A.
N.A.
13.3
N.A.
46.6
P-Site Similarity:
100
100
93.3
80
N.A.
86.6
86.6
N.A.
0
66.6
73.3
20
N.A.
N.A.
33.3
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
34
9
0
0
0
0
25
0
0
9
9
0
0
0
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
9
50
0
0
0
42
25
9
0
0
% D
% Glu:
0
9
0
0
0
0
25
9
9
0
25
17
0
0
75
% E
% Phe:
0
0
0
9
0
0
0
0
75
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
9
0
0
9
0
0
0
0
9
0
% I
% Lys:
0
0
0
0
75
0
0
0
0
34
0
0
0
17
9
% K
% Leu:
17
0
0
75
0
0
9
9
0
9
9
0
75
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
50
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
0
0
0
0
25
0
0
0
17
0
34
0
59
0
% Q
% Arg:
0
9
0
0
9
0
0
0
0
25
0
0
0
0
0
% R
% Ser:
0
17
59
0
0
0
9
17
0
0
0
0
0
9
0
% S
% Thr:
0
25
17
0
0
0
0
17
0
0
0
0
0
0
0
% T
% Val:
9
0
0
0
0
0
0
17
0
9
9
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _