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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPFFR1
All Species:
14.85
Human Site:
T181
Identified Species:
29.7
UniProt:
Q9GZQ6
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9GZQ6
NP_071429.1
430
47819
T181
C
P
S
A
V
T
L
T
V
T
R
E
E
H
H
Chimpanzee
Pan troglodytes
XP_521501
554
60714
T304
C
P
S
A
V
T
L
T
V
T
R
E
E
H
H
Rhesus Macaque
Macaca mulatta
Q9GK74
381
42711
G170
R
I
S
F
L
I
I
G
L
A
W
G
I
S
A
Dog
Lupus familis
XP_851935
470
51517
T217
C
P
S
A
V
T
L
T
V
T
R
Q
E
H
H
Cat
Felis silvestris
Mouse
Mus musculus
Q924H0
417
47431
V184
P
S
A
I
M
L
H
V
Q
E
E
K
Y
Y
R
Rat
Rattus norvegicus
Q9EP86
432
48305
T181
C
P
S
A
V
T
L
T
V
T
R
E
E
H
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508665
308
34974
T97
H
I
Y
L
A
P
L
T
L
I
V
V
M
Y
A
Chicken
Gallus gallus
Q9DDN6
385
43491
G174
R
I
S
F
L
I
I
G
V
A
W
A
V
S
A
Frog
Xenopus laevis
P70031
453
51139
I201
V
L
S
S
I
I
M
I
P
Y
L
V
Y
N
K
Zebra Danio
Brachydanio rerio
XP_698728
484
53989
E192
S
A
V
T
L
T
V
E
R
V
E
H
H
Y
M
Tiger Blowfish
Takifugu rubipres
NP_001092118
426
48303
V183
P
S
G
V
M
L
Q
V
T
K
E
Q
T
V
R
Fruit Fly
Dros. melanogaster
P25931
464
53506
I239
A
L
A
T
A
L
P
I
P
I
V
S
G
L
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.5
29
80
N.A.
49.7
86.3
N.A.
51.8
29.7
24
51
50.4
29.9
N.A.
N.A.
N.A.
Protein Similarity:
100
76.5
46
83.6
N.A.
66.5
90.9
N.A.
57.6
46.2
40.4
62.8
66.7
45
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
93.3
N.A.
0
100
N.A.
13.3
13.3
6.6
6.6
0
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
100
N.A.
26.6
100
N.A.
26.6
26.6
33.3
26.6
13.3
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
17
34
17
0
0
0
0
17
0
9
0
0
25
% A
% Cys:
34
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% D
% Glu:
0
0
0
0
0
0
0
9
0
9
25
25
34
0
0
% E
% Phe:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
0
0
17
0
0
0
9
9
0
0
% G
% His:
9
0
0
0
0
0
9
0
0
0
0
9
9
34
34
% H
% Ile:
0
25
0
9
9
25
17
17
0
17
0
0
9
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
9
0
9
0
0
9
% K
% Leu:
0
17
0
9
25
25
42
0
17
0
9
0
0
9
0
% L
% Met:
0
0
0
0
17
0
9
0
0
0
0
0
9
0
9
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% N
% Pro:
17
34
0
0
0
9
9
0
17
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
9
0
9
0
0
17
0
0
0
% Q
% Arg:
17
0
0
0
0
0
0
0
9
0
34
0
0
0
17
% R
% Ser:
9
17
59
9
0
0
0
0
0
0
0
9
0
17
0
% S
% Thr:
0
0
0
17
0
42
0
42
9
34
0
0
9
0
0
% T
% Val:
9
0
9
9
34
0
9
17
42
9
17
17
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
0
0
9
0
0
17
25
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _