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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: REXO4 All Species: 7.58
Human Site: S128 Identified Species: 12.82
UniProt: Q9GZR2 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.23
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZR2 NP_065118.2 422 46672 S128 A G K D Q E A S R G S V P S G
Chimpanzee Pan troglodytes XP_528522 404 44489 V126 K M D R K A P V P R T K A S G
Rhesus Macaque Macaca mulatta XP_001101121 422 46500 S128 A G K E Q E A S R G S V P S G
Dog Lupus familis XP_548392 428 46939 G126 T T D P G A T G S D S L A S G
Cat Felis silvestris
Mouse Mus musculus Q6PAQ4 432 47580 S138 Q R T E K A K S T R G S V T S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508485 438 48720 A140 D R T G G K S A K A A A P L E
Chicken Gallus gallus XP_001236410 416 45873 A124 D K R A K S C A D G S T P M A
Frog Xenopus laevis Q91560 421 46679 I125 G I T S V S A I A K G A K A P
Zebra Danio Brachydanio rerio XP_002665913 418 47625 Q147 K E Q S G H K Q F K A E K R K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396691 278 32474 S57 F R N L V F N S P S L N P D S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794891 360 40175 R125 K L K A S A P R N P K P K T K
Poplar Tree Populus trichocarpa XP_002300407 274 31114 R53 Q D S I L G K R K E R P D A E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q08237 289 32876 K68 D M V Y N M N K E I S K H E K
Red Bread Mold Neurospora crassa Q7S9B7 406 43643 Y127 S E S L A E A Y N L G L R G T
Conservation
Percent
Protein Identity: 100 94.3 93.1 68.4 N.A. 67.5 N.A. N.A. 55.7 49 50.7 45 N.A. N.A. 34.1 N.A. 35.7
Protein Similarity: 100 95.5 95.9 77.3 N.A. 77.5 N.A. N.A. 68 63.2 67.3 60.9 N.A. N.A. 47.3 N.A. 53
P-Site Identity: 100 13.3 93.3 20 N.A. 6.6 N.A. N.A. 6.6 20 6.6 0 N.A. N.A. 13.3 N.A. 6.6
P-Site Similarity: 100 26.6 100 26.6 N.A. 26.6 N.A. N.A. 40 40 13.3 13.3 N.A. N.A. 13.3 N.A. 13.3
Percent
Protein Identity: 32.2 N.A. N.A. N.A. 28.6 26.7
Protein Similarity: 45 N.A. N.A. N.A. 43.8 47.6
P-Site Identity: 0 N.A. N.A. N.A. 6.6 13.3
P-Site Similarity: 13.3 N.A. N.A. N.A. 6.6 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 0 0 15 8 29 29 15 8 8 15 15 15 15 8 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 22 8 15 8 0 0 0 0 8 8 0 0 8 8 0 % D
% Glu: 0 15 0 15 0 22 0 0 8 8 0 8 0 8 15 % E
% Phe: 8 0 0 0 0 8 0 0 8 0 0 0 0 0 0 % F
% Gly: 8 15 0 8 22 8 0 8 0 22 22 0 0 8 29 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 8 0 8 0 0 0 8 0 8 0 0 0 0 0 % I
% Lys: 22 8 22 0 22 8 22 8 15 15 8 15 22 0 22 % K
% Leu: 0 8 0 15 8 0 0 0 0 8 8 15 0 8 0 % L
% Met: 0 15 0 0 0 8 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 8 0 8 0 15 0 15 0 0 8 0 0 0 % N
% Pro: 0 0 0 8 0 0 15 0 15 8 0 15 36 0 8 % P
% Gln: 15 0 8 0 15 0 0 8 0 0 0 0 0 0 0 % Q
% Arg: 0 22 8 8 0 0 0 15 15 15 8 0 8 8 0 % R
% Ser: 8 0 15 15 8 15 8 29 8 8 36 8 0 29 15 % S
% Thr: 8 8 22 0 0 0 8 0 8 0 8 8 0 15 8 % T
% Val: 0 0 8 0 15 0 0 8 0 0 0 15 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _