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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
REXO4
All Species:
10.3
Human Site:
S131
Identified Species:
17.44
UniProt:
Q9GZR2
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9GZR2
NP_065118.2
422
46672
S131
D
Q
E
A
S
R
G
S
V
P
S
G
S
K
M
Chimpanzee
Pan troglodytes
XP_528522
404
44489
T129
R
K
A
P
V
P
R
T
K
A
S
G
A
E
H
Rhesus Macaque
Macaca mulatta
XP_001101121
422
46500
S131
E
Q
E
A
S
R
G
S
V
P
S
G
S
K
M
Dog
Lupus familis
XP_548392
428
46939
S129
P
G
A
T
G
S
D
S
L
A
S
G
S
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q6PAQ4
432
47580
G141
E
K
A
K
S
T
R
G
S
V
T
S
A
P
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508485
438
48720
A143
G
G
K
S
A
K
A
A
A
P
L
E
P
P
N
Chicken
Gallus gallus
XP_001236410
416
45873
S127
A
K
S
C
A
D
G
S
T
P
M
A
G
P
K
Frog
Xenopus laevis
Q91560
421
46679
G128
S
V
S
A
I
A
K
G
A
K
A
P
S
Q
A
Zebra Danio
Brachydanio rerio
XP_002665913
418
47625
A150
S
G
H
K
Q
F
K
A
E
K
R
K
N
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396691
278
32474
L60
L
V
F
N
S
P
S
L
N
P
D
S
G
K
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794891
360
40175
K128
A
S
A
P
R
N
P
K
P
K
T
K
N
S
N
Poplar Tree
Populus trichocarpa
XP_002300407
274
31114
R56
I
L
G
K
R
K
E
R
P
D
A
E
S
D
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08237
289
32876
S71
Y
N
M
N
K
E
I
S
K
H
E
K
D
K
L
Red Bread Mold
Neurospora crassa
Q7S9B7
406
43643
G130
L
A
E
A
Y
N
L
G
L
R
G
T
S
S
S
Conservation
Percent
Protein Identity:
100
94.3
93.1
68.4
N.A.
67.5
N.A.
N.A.
55.7
49
50.7
45
N.A.
N.A.
34.1
N.A.
35.7
Protein Similarity:
100
95.5
95.9
77.3
N.A.
77.5
N.A.
N.A.
68
63.2
67.3
60.9
N.A.
N.A.
47.3
N.A.
53
P-Site Identity:
100
13.3
93.3
26.6
N.A.
6.6
N.A.
N.A.
6.6
20
13.3
6.6
N.A.
N.A.
20
N.A.
0
P-Site Similarity:
100
40
100
33.3
N.A.
33.3
N.A.
N.A.
40
33.3
26.6
20
N.A.
N.A.
20
N.A.
13.3
Percent
Protein Identity:
32.2
N.A.
N.A.
N.A.
28.6
26.7
Protein Similarity:
45
N.A.
N.A.
N.A.
43.8
47.6
P-Site Identity:
6.6
N.A.
N.A.
N.A.
13.3
20
P-Site Similarity:
20
N.A.
N.A.
N.A.
20
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
8
29
29
15
8
8
15
15
15
15
8
15
0
8
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
8
8
0
0
8
8
0
8
8
8
% D
% Glu:
15
0
22
0
0
8
8
0
8
0
8
15
0
8
8
% E
% Phe:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
22
8
0
8
0
22
22
0
0
8
29
15
0
8
% G
% His:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
8
% H
% Ile:
8
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
22
8
22
8
15
15
8
15
22
0
22
0
36
15
% K
% Leu:
15
8
0
0
0
0
8
8
15
0
8
0
0
0
8
% L
% Met:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
15
% M
% Asn:
0
8
0
15
0
15
0
0
8
0
0
0
15
0
15
% N
% Pro:
8
0
0
15
0
15
8
0
15
36
0
8
8
29
0
% P
% Gln:
0
15
0
0
8
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
8
0
0
0
15
15
15
8
0
8
8
0
0
0
0
% R
% Ser:
15
8
15
8
29
8
8
36
8
0
29
15
43
15
8
% S
% Thr:
0
0
0
8
0
8
0
8
8
0
15
8
0
0
8
% T
% Val:
0
15
0
0
8
0
0
0
15
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _