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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: REXO4 All Species: 10.3
Human Site: S131 Identified Species: 17.44
UniProt: Q9GZR2 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZR2 NP_065118.2 422 46672 S131 D Q E A S R G S V P S G S K M
Chimpanzee Pan troglodytes XP_528522 404 44489 T129 R K A P V P R T K A S G A E H
Rhesus Macaque Macaca mulatta XP_001101121 422 46500 S131 E Q E A S R G S V P S G S K M
Dog Lupus familis XP_548392 428 46939 S129 P G A T G S D S L A S G S P G
Cat Felis silvestris
Mouse Mus musculus Q6PAQ4 432 47580 G141 E K A K S T R G S V T S A P T
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508485 438 48720 A143 G G K S A K A A A P L E P P N
Chicken Gallus gallus XP_001236410 416 45873 S127 A K S C A D G S T P M A G P K
Frog Xenopus laevis Q91560 421 46679 G128 S V S A I A K G A K A P S Q A
Zebra Danio Brachydanio rerio XP_002665913 418 47625 A150 S G H K Q F K A E K R K N K D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396691 278 32474 L60 L V F N S P S L N P D S G K E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794891 360 40175 K128 A S A P R N P K P K T K N S N
Poplar Tree Populus trichocarpa XP_002300407 274 31114 R56 I L G K R K E R P D A E S D K
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q08237 289 32876 S71 Y N M N K E I S K H E K D K L
Red Bread Mold Neurospora crassa Q7S9B7 406 43643 G130 L A E A Y N L G L R G T S S S
Conservation
Percent
Protein Identity: 100 94.3 93.1 68.4 N.A. 67.5 N.A. N.A. 55.7 49 50.7 45 N.A. N.A. 34.1 N.A. 35.7
Protein Similarity: 100 95.5 95.9 77.3 N.A. 77.5 N.A. N.A. 68 63.2 67.3 60.9 N.A. N.A. 47.3 N.A. 53
P-Site Identity: 100 13.3 93.3 26.6 N.A. 6.6 N.A. N.A. 6.6 20 13.3 6.6 N.A. N.A. 20 N.A. 0
P-Site Similarity: 100 40 100 33.3 N.A. 33.3 N.A. N.A. 40 33.3 26.6 20 N.A. N.A. 20 N.A. 13.3
Percent
Protein Identity: 32.2 N.A. N.A. N.A. 28.6 26.7
Protein Similarity: 45 N.A. N.A. N.A. 43.8 47.6
P-Site Identity: 6.6 N.A. N.A. N.A. 13.3 20
P-Site Similarity: 20 N.A. N.A. N.A. 20 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 8 29 29 15 8 8 15 15 15 15 8 15 0 8 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 8 8 0 0 8 8 0 8 8 8 % D
% Glu: 15 0 22 0 0 8 8 0 8 0 8 15 0 8 8 % E
% Phe: 0 0 8 0 0 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 22 8 0 8 0 22 22 0 0 8 29 15 0 8 % G
% His: 0 0 8 0 0 0 0 0 0 8 0 0 0 0 8 % H
% Ile: 8 0 0 0 8 0 8 0 0 0 0 0 0 0 0 % I
% Lys: 0 22 8 22 8 15 15 8 15 22 0 22 0 36 15 % K
% Leu: 15 8 0 0 0 0 8 8 15 0 8 0 0 0 8 % L
% Met: 0 0 8 0 0 0 0 0 0 0 8 0 0 0 15 % M
% Asn: 0 8 0 15 0 15 0 0 8 0 0 0 15 0 15 % N
% Pro: 8 0 0 15 0 15 8 0 15 36 0 8 8 29 0 % P
% Gln: 0 15 0 0 8 0 0 0 0 0 0 0 0 8 0 % Q
% Arg: 8 0 0 0 15 15 15 8 0 8 8 0 0 0 0 % R
% Ser: 15 8 15 8 29 8 8 36 8 0 29 15 43 15 8 % S
% Thr: 0 0 0 8 0 8 0 8 8 0 15 8 0 0 8 % T
% Val: 0 15 0 0 8 0 0 0 15 8 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _