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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: REXO4 All Species: 10.3
Human Site: S136 Identified Species: 17.44
UniProt: Q9GZR2 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZR2 NP_065118.2 422 46672 S136 R G S V P S G S K M D R R A P
Chimpanzee Pan troglodytes XP_528522 404 44489 A134 P R T K A S G A E H N K K G T
Rhesus Macaque Macaca mulatta XP_001101121 422 46500 S136 R G S V P S G S K M D R K A P
Dog Lupus familis XP_548392 428 46939 S134 S D S L A S G S P G K R K V P
Cat Felis silvestris
Mouse Mus musculus Q6PAQ4 432 47580 A146 T R G S V T S A P T D R K I L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508485 438 48720 P148 K A A A P L E P P N D R T A A
Chicken Gallus gallus XP_001236410 416 45873 G132 D G S T P M A G P K P R K A E
Frog Xenopus laevis Q91560 421 46679 S133 A K G A K A P S Q A T P T K A
Zebra Danio Brachydanio rerio XP_002665913 418 47625 N155 F K A E K R K N K D G K E K G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396691 278 32474 G65 P S L N P D S G K E N V K K K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794891 360 40175 N133 N P K P K T K N S N A S D K A
Poplar Tree Populus trichocarpa XP_002300407 274 31114 S61 K E R P D A E S D K S Q I N P
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q08237 289 32876 D76 E I S K H E K D K L E G K V F
Red Bread Mold Neurospora crassa Q7S9B7 406 43643 S135 N L G L R G T S S S S S S S H
Conservation
Percent
Protein Identity: 100 94.3 93.1 68.4 N.A. 67.5 N.A. N.A. 55.7 49 50.7 45 N.A. N.A. 34.1 N.A. 35.7
Protein Similarity: 100 95.5 95.9 77.3 N.A. 77.5 N.A. N.A. 68 63.2 67.3 60.9 N.A. N.A. 47.3 N.A. 53
P-Site Identity: 100 13.3 93.3 40 N.A. 13.3 N.A. N.A. 26.6 33.3 6.6 6.6 N.A. N.A. 13.3 N.A. 0
P-Site Similarity: 100 53.3 100 53.3 N.A. 33.3 N.A. N.A. 40 40 20 26.6 N.A. N.A. 26.6 N.A. 13.3
Percent
Protein Identity: 32.2 N.A. N.A. N.A. 28.6 26.7
Protein Similarity: 45 N.A. N.A. N.A. 43.8 47.6
P-Site Identity: 13.3 N.A. N.A. N.A. 13.3 6.6
P-Site Similarity: 33.3 N.A. N.A. N.A. 33.3 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 15 15 15 15 8 15 0 8 8 0 0 29 22 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 0 0 8 8 0 8 8 8 29 0 8 0 0 % D
% Glu: 8 8 0 8 0 8 15 0 8 8 8 0 8 0 8 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % F
% Gly: 0 22 22 0 0 8 29 15 0 8 8 8 0 8 8 % G
% His: 0 0 0 0 8 0 0 0 0 8 0 0 0 0 8 % H
% Ile: 0 8 0 0 0 0 0 0 0 0 0 0 8 8 0 % I
% Lys: 15 15 8 15 22 0 22 0 36 15 8 15 50 29 8 % K
% Leu: 0 8 8 15 0 8 0 0 0 8 0 0 0 0 8 % L
% Met: 0 0 0 0 0 8 0 0 0 15 0 0 0 0 0 % M
% Asn: 15 0 0 8 0 0 0 15 0 15 15 0 0 8 0 % N
% Pro: 15 8 0 15 36 0 8 8 29 0 8 8 0 0 29 % P
% Gln: 0 0 0 0 0 0 0 0 8 0 0 8 0 0 0 % Q
% Arg: 15 15 8 0 8 8 0 0 0 0 0 43 8 0 0 % R
% Ser: 8 8 36 8 0 29 15 43 15 8 15 15 8 8 0 % S
% Thr: 8 0 8 8 0 15 8 0 0 8 8 0 15 0 8 % T
% Val: 0 0 0 15 8 0 0 0 0 0 0 8 0 15 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _