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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: REXO4 All Species: 8.79
Human Site: S15 Identified Species: 14.87
UniProt: Q9GZR2 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZR2 NP_065118.2 422 46672 S15 A S K R A P S S P V A K P G P
Chimpanzee Pan troglodytes XP_528522 404 44489 S15 A S K R A P S S P V A K P G P
Rhesus Macaque Macaca mulatta XP_001101121 422 46500 S15 A S K G A P S S P V A K P G P
Dog Lupus familis XP_548392 428 46939 E13 N S M G G P G E P P A E P D L
Cat Felis silvestris
Mouse Mus musculus Q6PAQ4 432 47580 A19 S S L V V P T A E S G E M K T
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508485 438 48720 N24 S P K P P T G N S A P N P E R
Chicken Gallus gallus XP_001236410 416 45873 A13 A Q K G Q K A A A V A A X P R
Frog Xenopus laevis Q91560 421 46679 C13 V K K D Q S P C S G S L G K T
Zebra Danio Brachydanio rerio XP_002665913 418 47625 G30 Y N R K S Y K G D T W F F A T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396691 278 32474
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794891 360 40175 L15 S S N E Q D K L D T V S T T K
Poplar Tree Populus trichocarpa XP_002300407 274 31114
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q08237 289 32876
Red Bread Mold Neurospora crassa Q7S9B7 406 43643 E14 S N W K K L Q E K L K A P Q P
Conservation
Percent
Protein Identity: 100 94.3 93.1 68.4 N.A. 67.5 N.A. N.A. 55.7 49 50.7 45 N.A. N.A. 34.1 N.A. 35.7
Protein Similarity: 100 95.5 95.9 77.3 N.A. 77.5 N.A. N.A. 68 63.2 67.3 60.9 N.A. N.A. 47.3 N.A. 53
P-Site Identity: 100 100 93.3 33.3 N.A. 13.3 N.A. N.A. 13.3 26.6 6.6 0 N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 100 100 93.3 40 N.A. 40 N.A. N.A. 26.6 40 13.3 26.6 N.A. N.A. 0 N.A. 13.3
Percent
Protein Identity: 32.2 N.A. N.A. N.A. 28.6 26.7
Protein Similarity: 45 N.A. N.A. N.A. 43.8 47.6
P-Site Identity: 0 N.A. N.A. N.A. 0 13.3
P-Site Similarity: 0 N.A. N.A. N.A. 0 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 29 0 0 0 22 0 8 15 8 8 36 15 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 8 0 0 15 0 0 0 0 8 0 % D
% Glu: 0 0 0 8 0 0 0 15 8 0 0 15 0 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 8 8 0 0 % F
% Gly: 0 0 0 22 8 0 15 8 0 8 8 0 8 22 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 8 43 15 8 8 15 0 8 0 8 22 0 15 8 % K
% Leu: 0 0 8 0 0 8 0 8 0 8 0 8 0 0 8 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 8 15 8 0 0 0 0 8 0 0 0 8 0 0 0 % N
% Pro: 0 8 0 8 8 36 8 0 29 8 8 0 43 8 29 % P
% Gln: 0 8 0 0 22 0 8 0 0 0 0 0 0 8 0 % Q
% Arg: 0 0 8 15 0 0 0 0 0 0 0 0 0 0 15 % R
% Ser: 29 43 0 0 8 8 22 22 15 8 8 8 0 0 0 % S
% Thr: 0 0 0 0 0 8 8 0 0 15 0 0 8 8 22 % T
% Val: 8 0 0 8 8 0 0 0 0 29 8 0 0 0 0 % V
% Trp: 0 0 8 0 0 0 0 0 0 0 8 0 0 0 0 % W
% Tyr: 8 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _