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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
REXO4
All Species:
15.45
Human Site:
S226
Identified Species:
26.15
UniProt:
Q9GZR2
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9GZR2
NP_065118.2
422
46672
S226
Q
L
G
Q
S
E
G
S
V
S
L
S
L
V
K
Chimpanzee
Pan troglodytes
XP_528522
404
44489
S208
Q
L
G
Q
S
E
G
S
V
S
L
S
L
V
K
Rhesus Macaque
Macaca mulatta
XP_001101121
422
46500
S226
Q
L
G
Q
S
E
G
S
V
S
L
S
L
V
K
Dog
Lupus familis
XP_548392
428
46939
E228
R
Q
Q
L
G
Q
S
E
S
S
T
T
L
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q6PAQ4
432
47580
K236
R
K
R
L
G
Q
K
K
R
T
I
S
L
E
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508485
438
48720
Q244
L
E
E
D
Q
V
P
Q
V
E
K
V
L
V
K
Chicken
Gallus gallus
XP_001236410
416
45873
S225
E
A
G
Q
S
K
Q
S
V
E
Q
V
L
V
K
Frog
Xenopus laevis
Q91560
421
46679
T217
I
T
D
T
R
S
P
T
V
D
K
I
L
V
K
Zebra Danio
Brachydanio rerio
XP_002665913
418
47625
N216
L
A
K
C
D
P
K
N
T
E
K
M
L
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396691
278
32474
D125
C
E
M
V
G
I
G
D
G
T
E
S
M
L
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794891
360
40175
E193
K
C
V
A
L
D
C
E
M
V
G
I
G
H
E
Poplar Tree
Populus trichocarpa
XP_002300407
274
31114
E121
D
E
F
V
R
P
V
E
R
V
A
D
F
R
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08237
289
32876
K136
V
G
V
G
P
E
G
K
E
S
A
L
A
R
I
Red Bread Mold
Neurospora crassa
Q7S9B7
406
43643
T199
T
L
D
T
S
T
T
T
D
L
A
L
I
L
Q
Conservation
Percent
Protein Identity:
100
94.3
93.1
68.4
N.A.
67.5
N.A.
N.A.
55.7
49
50.7
45
N.A.
N.A.
34.1
N.A.
35.7
Protein Similarity:
100
95.5
95.9
77.3
N.A.
77.5
N.A.
N.A.
68
63.2
67.3
60.9
N.A.
N.A.
47.3
N.A.
53
P-Site Identity:
100
100
100
26.6
N.A.
20
N.A.
N.A.
26.6
53.3
26.6
20
N.A.
N.A.
13.3
N.A.
0
P-Site Similarity:
100
100
100
46.6
N.A.
46.6
N.A.
N.A.
26.6
66.6
33.3
26.6
N.A.
N.A.
33.3
N.A.
26.6
Percent
Protein Identity:
32.2
N.A.
N.A.
N.A.
28.6
26.7
Protein Similarity:
45
N.A.
N.A.
N.A.
43.8
47.6
P-Site Identity:
0
N.A.
N.A.
N.A.
20
13.3
P-Site Similarity:
0
N.A.
N.A.
N.A.
20
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
8
0
0
0
0
0
0
22
0
8
0
8
% A
% Cys:
8
8
0
8
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
15
8
8
8
0
8
8
8
0
8
0
0
0
% D
% Glu:
8
22
8
0
0
29
0
22
8
22
8
0
0
8
8
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
8
29
8
22
0
36
0
8
0
8
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
8
0
0
0
0
8
0
0
0
0
8
15
8
0
8
% I
% Lys:
8
8
8
0
0
8
15
15
0
0
22
0
0
0
65
% K
% Leu:
15
29
0
15
8
0
0
0
0
8
22
15
65
15
0
% L
% Met:
0
0
8
0
0
0
0
0
8
0
0
8
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
15
15
0
0
0
0
0
0
0
0
% P
% Gln:
22
8
8
29
8
15
8
8
0
0
8
0
0
0
8
% Q
% Arg:
15
0
8
0
15
0
0
0
15
0
0
0
0
15
0
% R
% Ser:
0
0
0
0
36
8
8
29
8
36
0
36
0
0
0
% S
% Thr:
8
8
0
15
0
8
8
15
8
15
8
8
0
0
8
% T
% Val:
8
0
15
15
0
8
8
0
43
15
0
15
0
58
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _