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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: REXO4 All Species: 16.36
Human Site: S228 Identified Species: 27.69
UniProt: Q9GZR2 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.31
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZR2 NP_065118.2 422 46672 S228 G Q S E G S V S L S L V K E Q
Chimpanzee Pan troglodytes XP_528522 404 44489 S210 G Q S E G S V S L S L V K E Q
Rhesus Macaque Macaca mulatta XP_001101121 422 46500 S228 G Q S E G S V S L S L V K E Q
Dog Lupus familis XP_548392 428 46939 S230 Q L G Q S E S S T T L V K E Q
Cat Felis silvestris
Mouse Mus musculus Q6PAQ4 432 47580 T238 R L G Q K K R T I S L E K E Q
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508485 438 48720 E246 E D Q V P Q V E K V L V K E Q
Chicken Gallus gallus XP_001236410 416 45873 E227 G Q S K Q S V E Q V L V K E K
Frog Xenopus laevis Q91560 421 46679 D219 D T R S P T V D K I L V K E R
Zebra Danio Brachydanio rerio XP_002665913 418 47625 E218 K C D P K N T E K M L V K E H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396691 278 32474 T127 M V G I G D G T E S M L A R I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794891 360 40175 V195 V A L D C E M V G I G H E G K
Poplar Tree Populus trichocarpa XP_002300407 274 31114 V123 F V R P V E R V A D F R T Q I
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q08237 289 32876 S138 V G P E G K E S A L A R I S I
Red Bread Mold Neurospora crassa Q7S9B7 406 43643 L201 D T S T T T D L A L I L Q A T
Conservation
Percent
Protein Identity: 100 94.3 93.1 68.4 N.A. 67.5 N.A. N.A. 55.7 49 50.7 45 N.A. N.A. 34.1 N.A. 35.7
Protein Similarity: 100 95.5 95.9 77.3 N.A. 77.5 N.A. N.A. 68 63.2 67.3 60.9 N.A. N.A. 47.3 N.A. 53
P-Site Identity: 100 100 100 40 N.A. 33.3 N.A. N.A. 40 60 33.3 26.6 N.A. N.A. 13.3 N.A. 0
P-Site Similarity: 100 100 100 53.3 N.A. 53.3 N.A. N.A. 40 73.3 46.6 33.3 N.A. N.A. 33.3 N.A. 26.6
Percent
Protein Identity: 32.2 N.A. N.A. N.A. 28.6 26.7
Protein Similarity: 45 N.A. N.A. N.A. 43.8 47.6
P-Site Identity: 0 N.A. N.A. N.A. 20 6.6
P-Site Similarity: 6.6 N.A. N.A. N.A. 20 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 0 22 0 8 0 8 8 0 % A
% Cys: 0 8 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 15 8 8 8 0 8 8 8 0 8 0 0 0 0 0 % D
% Glu: 8 0 0 29 0 22 8 22 8 0 0 8 8 65 0 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 29 8 22 0 36 0 8 0 8 0 8 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 8 % H
% Ile: 0 0 0 8 0 0 0 0 8 15 8 0 8 0 22 % I
% Lys: 8 0 0 8 15 15 0 0 22 0 0 0 65 0 15 % K
% Leu: 0 15 8 0 0 0 0 8 22 15 65 15 0 0 0 % L
% Met: 8 0 0 0 0 0 8 0 0 8 8 0 0 0 0 % M
% Asn: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 8 15 15 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 8 29 8 15 8 8 0 0 8 0 0 0 8 8 43 % Q
% Arg: 8 0 15 0 0 0 15 0 0 0 0 15 0 8 8 % R
% Ser: 0 0 36 8 8 29 8 36 0 36 0 0 0 8 0 % S
% Thr: 0 15 0 8 8 15 8 15 8 8 0 0 8 0 8 % T
% Val: 15 15 0 8 8 0 43 15 0 15 0 58 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _