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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: REXO4 All Species: 18.18
Human Site: S355 Identified Species: 30.77
UniProt: Q9GZR2 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZR2 NP_065118.2 422 46672 S355 Q K Y K P F K S Q V K S G R P
Chimpanzee Pan troglodytes XP_528522 404 44489 S337 Q K Y K P F K S Q V K S G R P
Rhesus Macaque Macaca mulatta XP_001101121 422 46500 S355 Q K Y K P F K S Q V K S G R P
Dog Lupus familis XP_548392 428 46939 S357 Q K Y K P F K S Q V K S G R P
Cat Felis silvestris
Mouse Mus musculus Q6PAQ4 432 47580 S365 Q K F K P F R S R V K S G R P
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508485 438 48720 G343 L K G R I L V G H A L H N D L
Chicken Gallus gallus XP_001236410 416 45873 L327 R I L V G H A L H N D L K V L
Frog Xenopus laevis Q91560 421 46679 Q346 Q K Y K P F K Q K V K S G R P
Zebra Danio Brachydanio rerio XP_002665913 418 47625 Q345 Q R Y K P F R Q K V K S S R P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396691 278 32474 H212 Y L S H P R K H L R D T S R F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794891 360 40175 L281 L K N D M K V L F L G Q P R K
Poplar Tree Populus trichocarpa XP_002300407 274 31114 G208 H L A A E F L G A K I Q S G E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q08237 289 32876 R223 S H P K S L L R D T S R H L P
Red Bread Mold Neurospora crassa Q7S9B7 406 43643 K328 A K Y S G F R K Y G H G P K P
Conservation
Percent
Protein Identity: 100 94.3 93.1 68.4 N.A. 67.5 N.A. N.A. 55.7 49 50.7 45 N.A. N.A. 34.1 N.A. 35.7
Protein Similarity: 100 95.5 95.9 77.3 N.A. 77.5 N.A. N.A. 68 63.2 67.3 60.9 N.A. N.A. 47.3 N.A. 53
P-Site Identity: 100 100 100 100 N.A. 80 N.A. N.A. 6.6 0 86.6 66.6 N.A. N.A. 20 N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 13.3 6.6 93.3 86.6 N.A. N.A. 26.6 N.A. 20
Percent
Protein Identity: 32.2 N.A. N.A. N.A. 28.6 26.7
Protein Similarity: 45 N.A. N.A. N.A. 43.8 47.6
P-Site Identity: 6.6 N.A. N.A. N.A. 13.3 26.6
P-Site Similarity: 6.6 N.A. N.A. N.A. 13.3 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 8 0 0 8 0 8 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 0 0 0 8 0 15 0 0 8 0 % D
% Glu: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 8 % E
% Phe: 0 0 8 0 0 65 0 0 8 0 0 0 0 0 8 % F
% Gly: 0 0 8 0 15 0 0 15 0 8 8 8 43 8 0 % G
% His: 8 8 0 8 0 8 0 8 15 0 8 8 8 0 0 % H
% Ile: 0 8 0 0 8 0 0 0 0 0 8 0 0 0 0 % I
% Lys: 0 65 0 58 0 8 43 8 15 8 50 0 8 8 8 % K
% Leu: 15 15 8 0 0 15 15 15 8 8 8 8 0 8 15 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 0 0 0 8 0 0 8 0 0 % N
% Pro: 0 0 8 0 58 0 0 0 0 0 0 0 15 0 65 % P
% Gln: 50 0 0 0 0 0 0 15 29 0 0 15 0 0 0 % Q
% Arg: 8 8 0 8 0 8 22 8 8 8 0 8 0 65 0 % R
% Ser: 8 0 8 8 8 0 0 36 0 0 8 50 22 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 8 0 8 0 0 0 % T
% Val: 0 0 0 8 0 0 15 0 0 50 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 50 0 0 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _