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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: REXO4 All Species: 26.97
Human Site: S359 Identified Species: 45.64
UniProt: Q9GZR2 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZR2 NP_065118.2 422 46672 S359 P F K S Q V K S G R P S L R L
Chimpanzee Pan troglodytes XP_528522 404 44489 S341 P F K S Q V K S G R P S L R L
Rhesus Macaque Macaca mulatta XP_001101121 422 46500 S359 P F K S Q V K S G R P S L R L
Dog Lupus familis XP_548392 428 46939 S361 P F K S Q V K S G R P S L K L
Cat Felis silvestris
Mouse Mus musculus Q6PAQ4 432 47580 S369 P F R S R V K S G R P S L K R
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508485 438 48720 H347 I L V G H A L H N D L K I L L
Chicken Gallus gallus XP_001236410 416 45873 L331 G H A L H N D L K V L F L D H
Frog Xenopus laevis Q91560 421 46679 S350 P F K Q K V K S G R P S L K L
Zebra Danio Brachydanio rerio XP_002665913 418 47625 S349 P F R Q K V K S S R P A L R N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396691 278 32474 T216 P R K H L R D T S R F K T F R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794891 360 40175 Q285 M K V L F L G Q P R K L I R D
Poplar Tree Populus trichocarpa XP_002300407 274 31114 Q212 E F L G A K I Q S G E H C P I
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q08237 289 32876 R227 S L L R D T S R H L P F R K L
Red Bread Mold Neurospora crassa Q7S9B7 406 43643 G332 G F R K Y G H G P K P S L R V
Conservation
Percent
Protein Identity: 100 94.3 93.1 68.4 N.A. 67.5 N.A. N.A. 55.7 49 50.7 45 N.A. N.A. 34.1 N.A. 35.7
Protein Similarity: 100 95.5 95.9 77.3 N.A. 77.5 N.A. N.A. 68 63.2 67.3 60.9 N.A. N.A. 47.3 N.A. 53
P-Site Identity: 100 100 100 93.3 N.A. 73.3 N.A. N.A. 6.6 6.6 80 60 N.A. N.A. 20 N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 93.3 N.A. N.A. 13.3 6.6 93.3 80 N.A. N.A. 26.6 N.A. 26.6
Percent
Protein Identity: 32.2 N.A. N.A. N.A. 28.6 26.7
Protein Similarity: 45 N.A. N.A. N.A. 43.8 47.6
P-Site Identity: 6.6 N.A. N.A. N.A. 13.3 33.3
P-Site Similarity: 13.3 N.A. N.A. N.A. 20 53.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 8 8 0 0 0 0 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 0 0 0 8 0 15 0 0 8 0 0 0 8 8 % D
% Glu: 8 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % E
% Phe: 0 65 0 0 8 0 0 0 0 0 8 15 0 8 0 % F
% Gly: 15 0 0 15 0 8 8 8 43 8 0 0 0 0 0 % G
% His: 0 8 0 8 15 0 8 8 8 0 0 8 0 0 8 % H
% Ile: 8 0 0 0 0 0 8 0 0 0 0 0 15 0 8 % I
% Lys: 0 8 43 8 15 8 50 0 8 8 8 15 0 29 0 % K
% Leu: 0 15 15 15 8 8 8 8 0 8 15 8 65 8 50 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 8 0 0 8 0 0 0 0 0 8 % N
% Pro: 58 0 0 0 0 0 0 0 15 0 65 0 0 8 0 % P
% Gln: 0 0 0 15 29 0 0 15 0 0 0 0 0 0 0 % Q
% Arg: 0 8 22 8 8 8 0 8 0 65 0 0 8 43 15 % R
% Ser: 8 0 0 36 0 0 8 50 22 0 0 50 0 0 0 % S
% Thr: 0 0 0 0 0 8 0 8 0 0 0 0 8 0 0 % T
% Val: 0 0 15 0 0 50 0 0 0 8 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _