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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
REXO4
All Species:
25.15
Human Site:
S363
Identified Species:
42.56
UniProt:
Q9GZR2
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9GZR2
NP_065118.2
422
46672
S363
Q
V
K
S
G
R
P
S
L
R
L
L
S
E
K
Chimpanzee
Pan troglodytes
XP_528522
404
44489
S345
Q
V
K
S
G
R
P
S
L
R
L
L
S
E
K
Rhesus Macaque
Macaca mulatta
XP_001101121
422
46500
S363
Q
V
K
S
G
R
P
S
L
R
L
L
S
E
K
Dog
Lupus familis
XP_548392
428
46939
S365
Q
V
K
S
G
R
P
S
L
K
L
L
A
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q6PAQ4
432
47580
S373
R
V
K
S
G
R
P
S
L
K
R
L
S
E
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508485
438
48720
K351
H
A
L
H
N
D
L
K
I
L
L
L
D
H
P
Chicken
Gallus gallus
XP_001236410
416
45873
F335
H
N
D
L
K
V
L
F
L
D
H
P
K
K
K
Frog
Xenopus laevis
Q91560
421
46679
S354
K
V
K
S
G
R
P
S
L
K
L
L
C
E
K
Zebra Danio
Brachydanio rerio
XP_002665913
418
47625
A353
K
V
K
S
S
R
P
A
L
R
N
L
C
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396691
278
32474
K220
L
R
D
T
S
R
F
K
T
F
R
Q
L
S
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794891
360
40175
L289
F
L
G
Q
P
R
K
L
I
R
D
T
A
S
Y
Poplar Tree
Populus trichocarpa
XP_002300407
274
31114
H216
A
K
I
Q
S
G
E
H
C
P
I
E
D
A
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08237
289
32876
F231
D
T
S
R
H
L
P
F
R
K
L
Y
A
K
G
Red Bread Mold
Neurospora crassa
Q7S9B7
406
43643
S336
Y
G
H
G
P
K
P
S
L
R
V
L
A
K
E
Conservation
Percent
Protein Identity:
100
94.3
93.1
68.4
N.A.
67.5
N.A.
N.A.
55.7
49
50.7
45
N.A.
N.A.
34.1
N.A.
35.7
Protein Similarity:
100
95.5
95.9
77.3
N.A.
77.5
N.A.
N.A.
68
63.2
67.3
60.9
N.A.
N.A.
47.3
N.A.
53
P-Site Identity:
100
100
100
80
N.A.
80
N.A.
N.A.
13.3
13.3
80
53.3
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
N.A.
N.A.
20
20
93.3
73.3
N.A.
N.A.
20
N.A.
33.3
Percent
Protein Identity:
32.2
N.A.
N.A.
N.A.
28.6
26.7
Protein Similarity:
45
N.A.
N.A.
N.A.
43.8
47.6
P-Site Identity:
0
N.A.
N.A.
N.A.
13.3
33.3
P-Site Similarity:
13.3
N.A.
N.A.
N.A.
33.3
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
0
8
0
0
0
0
29
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
15
0
0
% C
% Asp:
8
0
15
0
0
8
0
0
0
8
8
0
15
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
0
0
0
8
0
43
8
% E
% Phe:
8
0
0
0
0
0
8
15
0
8
0
0
0
0
0
% F
% Gly:
0
8
8
8
43
8
0
0
0
0
0
0
0
0
8
% G
% His:
15
0
8
8
8
0
0
8
0
0
8
0
0
8
0
% H
% Ile:
0
0
8
0
0
0
0
0
15
0
8
0
0
0
0
% I
% Lys:
15
8
50
0
8
8
8
15
0
29
0
0
8
22
43
% K
% Leu:
8
8
8
8
0
8
15
8
65
8
50
65
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
8
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
15
0
65
0
0
8
0
8
0
0
8
% P
% Gln:
29
0
0
15
0
0
0
0
0
0
0
8
0
0
8
% Q
% Arg:
8
8
0
8
0
65
0
0
8
43
15
0
0
8
22
% R
% Ser:
0
0
8
50
22
0
0
50
0
0
0
0
29
15
0
% S
% Thr:
0
8
0
8
0
0
0
0
8
0
0
8
0
0
0
% T
% Val:
0
50
0
0
0
8
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _