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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: REXO4 All Species: 14.85
Human Site: T147 Identified Species: 25.13
UniProt: Q9GZR2 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZR2 NP_065118.2 422 46672 T147 R R A P V P R T K A S G T E H
Chimpanzee Pan troglodytes XP_528522 404 44489 T145 K K G T K E R T D G D I V P E
Rhesus Macaque Macaca mulatta XP_001101121 422 46500 S147 R K A P G P R S K A S G A E H
Dog Lupus familis XP_548392 428 46939 T145 R K V P A P P T K A S R A E H
Cat Felis silvestris
Mouse Mus musculus Q6PAQ4 432 47580 T157 R K I L V P P T D T S G T E Q
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508485 438 48720 S159 R T A A L G K S P V G A A G N
Chicken Gallus gallus XP_001236410 416 45873 N143 R K A E E D K N W N G T K S D
Frog Xenopus laevis Q91560 421 46679 S144 P T K A A E K S D E V S K G K
Zebra Danio Brachydanio rerio XP_002665913 418 47625 K166 K E K G M N K K S K A E E E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396691 278 32474 H76 V K K K S S P H Q K S R K K H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794891 360 40175 K144 S D K A V E K K E N E I W F D
Poplar Tree Populus trichocarpa XP_002300407 274 31114 T72 Q I N P L I P T N D D F S V T
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q08237 289 32876 P87 G K V F E F N P N K A N T S T
Red Bread Mold Neurospora crassa Q7S9B7 406 43643 L146 S S S H I P L L S T L P P A I
Conservation
Percent
Protein Identity: 100 94.3 93.1 68.4 N.A. 67.5 N.A. N.A. 55.7 49 50.7 45 N.A. N.A. 34.1 N.A. 35.7
Protein Similarity: 100 95.5 95.9 77.3 N.A. 77.5 N.A. N.A. 68 63.2 67.3 60.9 N.A. N.A. 47.3 N.A. 53
P-Site Identity: 100 13.3 73.3 60 N.A. 53.3 N.A. N.A. 13.3 13.3 0 6.6 N.A. N.A. 13.3 N.A. 6.6
P-Site Similarity: 100 26.6 86.6 66.6 N.A. 60 N.A. N.A. 40 26.6 13.3 33.3 N.A. N.A. 33.3 N.A. 20
Percent
Protein Identity: 32.2 N.A. N.A. N.A. 28.6 26.7
Protein Similarity: 45 N.A. N.A. N.A. 43.8 47.6
P-Site Identity: 13.3 N.A. N.A. N.A. 6.6 6.6
P-Site Similarity: 33.3 N.A. N.A. N.A. 20 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 29 22 15 0 0 0 0 22 15 8 22 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 8 0 0 22 8 15 0 0 0 15 % D
% Glu: 0 8 0 8 15 22 0 0 8 8 8 8 8 36 15 % E
% Phe: 0 0 0 8 0 8 0 0 0 0 0 8 0 8 0 % F
% Gly: 8 0 8 8 8 8 0 0 0 8 15 22 0 15 0 % G
% His: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 29 % H
% Ile: 0 8 8 0 8 8 0 0 0 0 0 15 0 0 8 % I
% Lys: 15 50 29 8 8 0 36 15 22 22 0 0 22 8 8 % K
% Leu: 0 0 0 8 15 0 8 8 0 0 8 0 0 0 0 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 8 8 8 15 15 0 8 0 0 8 % N
% Pro: 8 0 0 29 0 36 29 8 8 0 0 8 8 8 0 % P
% Gln: 8 0 0 0 0 0 0 0 8 0 0 0 0 0 8 % Q
% Arg: 43 8 0 0 0 0 22 0 0 0 0 15 0 0 0 % R
% Ser: 15 8 8 0 8 8 0 22 15 0 36 8 8 15 0 % S
% Thr: 0 15 0 8 0 0 0 36 0 15 0 8 22 0 15 % T
% Val: 8 0 15 0 22 0 0 0 0 8 8 0 8 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 0 8 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _