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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: REXO4 All Species: 29.7
Human Site: T347 Identified Species: 50.26
UniProt: Q9GZR2 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZR2 NP_065118.2 422 46672 T347 P K K K I R D T Q K Y K P F K
Chimpanzee Pan troglodytes XP_528522 404 44489 T329 P K K K I R D T Q K Y K P F K
Rhesus Macaque Macaca mulatta XP_001101121 422 46500 T347 P K K K I R D T Q K Y K P F K
Dog Lupus familis XP_548392 428 46939 T349 P K K K I R D T Q K Y K P F K
Cat Felis silvestris
Mouse Mus musculus Q6PAQ4 432 47580 T357 P K K K I R D T Q K F K P F R
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508485 438 48720 L335 V Q Q E V A N L L K G R I L V
Chicken Gallus gallus XP_001236410 416 45873 G319 E V A D I L N G R I L V G H A
Frog Xenopus laevis Q91560 421 46679 T338 P K K A I R D T Q K Y K P F K
Zebra Danio Brachydanio rerio XP_002665913 418 47625 T337 P K K M I R D T Q R Y K P F R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396691 278 32474 L204 L K Y D L D V L Y L S H P R K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794891 360 40175 A273 D R I L V G H A L K N D M K V
Poplar Tree Populus trichocarpa XP_002300407 274 31114 R200 G R R R K A L R H L A A E F L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q08237 289 32876 L215 H D L E A L M L S H P K S L L
Red Bread Mold Neurospora crassa Q7S9B7 406 43643 T320 P H R D I R D T A K Y S G F R
Conservation
Percent
Protein Identity: 100 94.3 93.1 68.4 N.A. 67.5 N.A. N.A. 55.7 49 50.7 45 N.A. N.A. 34.1 N.A. 35.7
Protein Similarity: 100 95.5 95.9 77.3 N.A. 77.5 N.A. N.A. 68 63.2 67.3 60.9 N.A. N.A. 47.3 N.A. 53
P-Site Identity: 100 100 100 100 N.A. 86.6 N.A. N.A. 6.6 6.6 93.3 80 N.A. N.A. 20 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 46.6 20 93.3 93.3 N.A. N.A. 26.6 N.A. 20
Percent
Protein Identity: 32.2 N.A. N.A. N.A. 28.6 26.7
Protein Similarity: 45 N.A. N.A. N.A. 43.8 47.6
P-Site Identity: 6.6 N.A. N.A. N.A. 6.6 53.3
P-Site Similarity: 26.6 N.A. N.A. N.A. 13.3 66.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 8 15 0 8 8 0 8 8 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 0 22 0 8 58 0 0 0 0 8 0 0 0 % D
% Glu: 8 0 0 15 0 0 0 0 0 0 0 0 8 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 0 0 65 0 % F
% Gly: 8 0 0 0 0 8 0 8 0 0 8 0 15 0 0 % G
% His: 8 8 0 0 0 0 8 0 8 8 0 8 0 8 0 % H
% Ile: 0 0 8 0 65 0 0 0 0 8 0 0 8 0 0 % I
% Lys: 0 58 50 36 8 0 0 0 0 65 0 58 0 8 43 % K
% Leu: 8 0 8 8 8 15 8 22 15 15 8 0 0 15 15 % L
% Met: 0 0 0 8 0 0 8 0 0 0 0 0 8 0 0 % M
% Asn: 0 0 0 0 0 0 15 0 0 0 8 0 0 0 0 % N
% Pro: 58 0 0 0 0 0 0 0 0 0 8 0 58 0 0 % P
% Gln: 0 8 8 0 0 0 0 0 50 0 0 0 0 0 0 % Q
% Arg: 0 15 15 8 0 58 0 8 8 8 0 8 0 8 22 % R
% Ser: 0 0 0 0 0 0 0 0 8 0 8 8 8 0 0 % S
% Thr: 0 0 0 0 0 0 0 58 0 0 0 0 0 0 0 % T
% Val: 8 8 0 0 15 0 8 0 0 0 0 8 0 0 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 0 8 0 50 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _