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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: REXO4 All Species: 10.3
Human Site: T413 Identified Species: 17.44
UniProt: Q9GZR2 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.23
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZR2 NP_065118.2 422 46672 T413 R D R R P L L T A P D H C S D
Chimpanzee Pan troglodytes XP_528522 404 44489 T395 R D R R P L L T A P D H C S D
Rhesus Macaque Macaca mulatta XP_001101121 422 46500 T413 R D R R P L L T A P D H C S D
Dog Lupus familis XP_548392 428 46939 P415 Q D R H P T A P T P D S S S V
Cat Felis silvestris
Mouse Mus musculus Q6PAQ4 432 47580 A423 A N R R A P A A T P Q H R I K
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508485 438 48720 S401 V Q K A E H C S V Q D A Q A A
Chicken Gallus gallus XP_001236410 416 45873 D385 S E H C S I Q D A Q A A M R L
Frog Xenopus laevis Q91560 421 46679 M404 K A K Y T G V M P V D R K S K
Zebra Danio Brachydanio rerio XP_002665913 418 47625 F403 K A M R G G T F K K S P R K P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396691 278 32474 W270 Y M L Y K N K W E S E L Y S K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794891 360 40175 L339 D A Q T A M R L Y T L H R T A
Poplar Tree Populus trichocarpa XP_002300407 274 31114 D266 T N E G G A L D V N R V A I I
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q08237 289 32876 E281 K K E K T E F E K I H R N T F
Red Bread Mold Neurospora crassa Q7S9B7 406 43643 Q386 S N R Y E E G Q A K K G G N G
Conservation
Percent
Protein Identity: 100 94.3 93.1 68.4 N.A. 67.5 N.A. N.A. 55.7 49 50.7 45 N.A. N.A. 34.1 N.A. 35.7
Protein Similarity: 100 95.5 95.9 77.3 N.A. 77.5 N.A. N.A. 68 63.2 67.3 60.9 N.A. N.A. 47.3 N.A. 53
P-Site Identity: 100 100 100 40 N.A. 26.6 N.A. N.A. 6.6 6.6 13.3 6.6 N.A. N.A. 6.6 N.A. 6.6
P-Site Similarity: 100 100 100 46.6 N.A. 33.3 N.A. N.A. 26.6 20 33.3 13.3 N.A. N.A. 13.3 N.A. 26.6
Percent
Protein Identity: 32.2 N.A. N.A. N.A. 28.6 26.7
Protein Similarity: 45 N.A. N.A. N.A. 43.8 47.6
P-Site Identity: 6.6 N.A. N.A. N.A. 0 13.3
P-Site Similarity: 13.3 N.A. N.A. N.A. 20 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 22 0 8 15 8 15 8 36 0 8 15 8 8 15 % A
% Cys: 0 0 0 8 0 0 8 0 0 0 0 0 22 0 0 % C
% Asp: 8 29 0 0 0 0 0 15 0 0 43 0 0 0 22 % D
% Glu: 0 8 15 0 15 15 0 8 8 0 8 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 8 8 0 0 0 0 0 0 8 % F
% Gly: 0 0 0 8 15 15 8 0 0 0 0 8 8 0 8 % G
% His: 0 0 8 8 0 8 0 0 0 0 8 36 0 0 0 % H
% Ile: 0 0 0 0 0 8 0 0 0 8 0 0 0 15 8 % I
% Lys: 22 8 15 8 8 0 8 0 15 15 8 0 8 8 22 % K
% Leu: 0 0 8 0 0 22 29 8 0 0 8 8 0 0 8 % L
% Met: 0 8 8 0 0 8 0 8 0 0 0 0 8 0 0 % M
% Asn: 0 22 0 0 0 8 0 0 0 8 0 0 8 8 0 % N
% Pro: 0 0 0 0 29 8 0 8 8 36 0 8 0 0 8 % P
% Gln: 8 8 8 0 0 0 8 8 0 15 8 0 8 0 0 % Q
% Arg: 22 0 43 36 0 0 8 0 0 0 8 15 22 8 0 % R
% Ser: 15 0 0 0 8 0 0 8 0 8 8 8 8 43 0 % S
% Thr: 8 0 0 8 15 8 8 22 15 8 0 0 0 15 0 % T
% Val: 8 0 0 0 0 0 8 0 15 8 0 8 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 22 0 0 0 0 8 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _