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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DNAI2
All Species:
17.88
Human Site:
S486
Identified Species:
32.78
UniProt:
Q9GZS0
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9GZS0
NP_075462.3
605
68851
S486
L
E
V
S
P
G
L
S
T
L
Q
R
N
E
K
Chimpanzee
Pan troglodytes
XP_001168154
605
68753
S486
L
E
V
S
P
G
L
S
T
L
Q
R
N
E
K
Rhesus Macaque
Macaca mulatta
XP_001088046
595
67488
A486
Q
R
N
E
K
N
I
A
S
S
M
F
E
R
E
Dog
Lupus familis
XP_540403
594
67850
C486
L
E
V
S
N
G
L
C
T
L
Q
R
N
E
K
Cat
Felis silvestris
Mouse
Mus musculus
A2AC93
623
70949
S486
L
E
V
S
S
S
L
S
T
L
Q
R
N
E
K
Rat
Rattus norvegicus
Q66HC9
619
70300
S486
L
E
V
S
S
S
L
S
T
L
Q
R
N
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511012
488
55688
T403
S
A
M
F
E
R
E
T
R
R
E
K
I
L
E
Chicken
Gallus gallus
XP_415701
608
69151
C486
L
E
I
S
S
G
L
C
T
L
Q
R
N
E
K
Frog
Xenopus laevis
NP_001089510
587
68015
Y486
M
E
L
S
K
G
L
Y
T
L
Q
R
N
E
R
Zebra Danio
Brachydanio rerio
XP_001343873
624
71808
C488
L
E
I
S
S
G
L
C
S
L
Q
K
N
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648497
576
65695
V484
V
E
V
S
D
N
M
V
M
S
A
K
N
D
K
Honey Bee
Apis mellifera
XP_395637
518
59671
D433
D
G
T
L
D
I
W
D
L
L
I
Q
Q
D
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796667
599
68453
C485
L
E
L
S
S
G
L
C
T
M
Q
R
N
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
92.5
85.9
N.A.
83.4
83.3
N.A.
54.2
67.9
69.4
66
N.A.
44.7
42.6
N.A.
65.9
Protein Similarity:
100
99.3
94.8
91.2
N.A.
90.6
91.5
N.A.
64.3
81.9
83.3
79.3
N.A.
62.4
59.3
N.A.
78.5
P-Site Identity:
100
100
0
86.6
N.A.
86.6
80
N.A.
0
80
66.6
66.6
N.A.
33.3
6.6
N.A.
73.3
P-Site Similarity:
100
100
26.6
86.6
N.A.
86.6
86.6
N.A.
33.3
86.6
86.6
86.6
N.A.
60
20
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
8
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
31
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
16
0
0
8
0
0
0
0
0
16
0
% D
% Glu:
0
77
0
8
8
0
8
0
0
0
8
0
8
70
16
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
8
0
0
0
54
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
16
0
0
8
8
0
0
0
8
0
8
0
0
% I
% Lys:
0
0
0
0
16
0
0
0
0
0
0
24
0
0
62
% K
% Leu:
62
0
16
8
0
0
70
0
8
70
0
0
0
8
0
% L
% Met:
8
0
8
0
0
0
8
0
8
8
8
0
0
0
0
% M
% Asn:
0
0
8
0
8
16
0
0
0
0
0
0
77
0
0
% N
% Pro:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
70
8
8
0
0
% Q
% Arg:
0
8
0
0
0
8
0
0
8
8
0
62
0
8
16
% R
% Ser:
8
0
0
77
39
16
0
31
16
16
0
0
0
0
8
% S
% Thr:
0
0
8
0
0
0
0
8
62
0
0
0
0
0
0
% T
% Val:
8
0
47
0
0
0
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _