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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DNAI2 All Species: 35.76
Human Site: T246 Identified Species: 65.56
UniProt: Q9GZS0 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZS0 NP_075462.3 605 68851 T246 G Q I A C W D T R K G S L V A
Chimpanzee Pan troglodytes XP_001168154 605 68753 T246 G Q I A C W D T R K G S L V A
Rhesus Macaque Macaca mulatta XP_001088046 595 67488 T246 G Q I A C W D T R K G S L V A
Dog Lupus familis XP_540403 594 67850 T246 G Q L A C W D T R K G S L V A
Cat Felis silvestris
Mouse Mus musculus A2AC93 623 70949 T246 G Q I A C W D T R K G S L V A
Rat Rattus norvegicus Q66HC9 619 70300 T246 G Q I A C W D T R K G S L V A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511012 488 55688 Q172 V Y G A I W L Q S K T G T E C
Chicken Gallus gallus XP_415701 608 69151 T246 G Q M A Y W D T R K G G L P V
Frog Xenopus laevis NP_001089510 587 68015 T246 G Q I A Y W D T R K G G N P V
Zebra Danio Brachydanio rerio XP_001343873 624 71808 T248 G Q I A Y W D T R K G S Q P V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648497 576 65695 H244 V A A W D T R H G K L P V M I
Honey Bee Apis mellifera XP_395637 518 59671 N202 I W D V E N P N I P C V T L K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796667 599 68453 T245 G Q V A F W D T R K G S Q A V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 92.5 85.9 N.A. 83.4 83.3 N.A. 54.2 67.9 69.4 66 N.A. 44.7 42.6 N.A. 65.9
Protein Similarity: 100 99.3 94.8 91.2 N.A. 90.6 91.5 N.A. 64.3 81.9 83.3 79.3 N.A. 62.4 59.3 N.A. 78.5
P-Site Identity: 100 100 100 93.3 N.A. 100 100 N.A. 20 66.6 66.6 73.3 N.A. 6.6 0 N.A. 66.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 20 73.3 66.6 73.3 N.A. 20 6.6 N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 85 0 0 0 0 0 0 0 0 0 8 47 % A
% Cys: 0 0 0 0 47 0 0 0 0 0 8 0 0 0 8 % C
% Asp: 0 0 8 0 8 0 77 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 8 0 0 0 0 0 0 0 0 8 0 % E
% Phe: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 77 0 8 0 0 0 0 0 8 0 77 24 0 0 0 % G
% His: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % H
% Ile: 8 0 54 0 8 0 0 0 8 0 0 0 0 0 8 % I
% Lys: 0 0 0 0 0 0 0 0 0 93 0 0 0 0 8 % K
% Leu: 0 0 8 0 0 0 8 0 0 0 8 0 54 8 0 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 0 0 0 8 0 8 0 0 0 0 8 0 0 % N
% Pro: 0 0 0 0 0 0 8 0 0 8 0 8 0 24 0 % P
% Gln: 0 77 0 0 0 0 0 8 0 0 0 0 16 0 0 % Q
% Arg: 0 0 0 0 0 0 8 0 77 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 8 0 0 62 0 0 0 % S
% Thr: 0 0 0 0 0 8 0 77 0 0 8 0 16 0 0 % T
% Val: 16 0 8 8 0 0 0 0 0 0 0 8 8 47 31 % V
% Trp: 0 8 0 8 0 85 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 24 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _