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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POLR1E All Species: 4.55
Human Site: S19 Identified Species: 11.11
UniProt: Q9GZS1 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZS1 NP_071935.1 481 53962 S19 R D I P S C H S P S P G F S H
Chimpanzee Pan troglodytes XP_001169764 477 53423 S19 R D I P S C H S P S P G F S H
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_531998 419 47056
Cat Felis silvestris
Mouse Mus musculus Q8K202 482 54015 L21 G D T E T E A L Q S A R W L Y
Rat Rattus norvegicus NP_001101408 434 48751
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517086 183 20540
Chicken Gallus gallus XP_424416 341 38462
Frog Xenopus laevis Q6GLI9 419 47348
Zebra Danio Brachydanio rerio NP_001018540 413 46491
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793654 285 32322
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 N.A. 75 N.A. 53.3 67.1 N.A. 25.9 38.8 46.5 37.2 N.A. N.A. N.A. N.A. 25.1
Protein Similarity: 100 98.9 N.A. 81.6 N.A. 67.2 79.2 N.A. 32.2 54.2 63.6 59.6 N.A. N.A. N.A. N.A. 37.8
P-Site Identity: 100 100 N.A. 0 N.A. 13.3 0 N.A. 0 0 0 0 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 N.A. 0 N.A. 33.3 0 N.A. 0 0 0 0 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 10 0 0 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 20 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 30 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 10 0 10 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 20 0 0 % F
% Gly: 10 0 0 0 0 0 0 0 0 0 0 20 0 0 0 % G
% His: 0 0 0 0 0 0 20 0 0 0 0 0 0 0 20 % H
% Ile: 0 0 20 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 10 0 0 0 0 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 20 0 0 0 0 20 0 20 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % Q
% Arg: 20 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % R
% Ser: 0 0 0 0 20 0 0 20 0 30 0 0 0 20 0 % S
% Thr: 0 0 10 0 10 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _