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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POLR1E All Species: 0.91
Human Site: S327 Identified Species: 2.22
UniProt: Q9GZS1 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZS1 NP_071935.1 481 53962 S327 E A L K S L P S D V E S R D R
Chimpanzee Pan troglodytes XP_001169764 477 53423 E326 K S L P S D V E S R D R Q A R
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_531998 419 47056 K268 K S L P S D E K S R D R Q A R
Cat Felis silvestris
Mouse Mus musculus Q8K202 482 54015 I328 E M L K S L P I D E V H R N R
Rat Rattus norvegicus NP_001101408 434 48751 V283 K S L P A D E V Q R N R Q A R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517086 183 20540 S32 S N G R L Q N S A N V N F T L
Chicken Gallus gallus XP_424416 341 38462 A190 N I T P E E I A K K T E E K R
Frog Xenopus laevis Q6GLI9 419 47348 E268 G L R E I K D E K A L D H Q A
Zebra Danio Brachydanio rerio NP_001018540 413 46491 R262 L S K D E A D R D R Q C R C A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793654 285 32322 R134 S L A E K K D R L T E A F G S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 N.A. 75 N.A. 53.3 67.1 N.A. 25.9 38.8 46.5 37.2 N.A. N.A. N.A. N.A. 25.1
Protein Similarity: 100 98.9 N.A. 81.6 N.A. 67.2 79.2 N.A. 32.2 54.2 63.6 59.6 N.A. N.A. N.A. N.A. 37.8
P-Site Identity: 100 20 N.A. 20 N.A. 60 13.3 N.A. 6.6 6.6 0 13.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 46.6 N.A. 46.6 N.A. 66.6 40 N.A. 20 13.3 6.6 26.6 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 0 10 10 0 10 10 10 0 10 0 30 20 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 10 0 10 0 % C
% Asp: 0 0 0 10 0 30 30 0 30 0 20 10 0 10 0 % D
% Glu: 20 0 0 20 20 10 20 20 0 10 20 10 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 20 0 0 % F
% Gly: 10 0 10 0 0 0 0 0 0 0 0 0 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 10 10 0 0 % H
% Ile: 0 10 0 0 10 0 10 10 0 0 0 0 0 0 0 % I
% Lys: 30 0 10 20 10 20 0 10 20 10 0 0 0 10 0 % K
% Leu: 10 20 50 0 10 20 0 0 10 0 10 0 0 0 10 % L
% Met: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 10 0 0 0 0 10 0 0 10 10 10 0 10 0 % N
% Pro: 0 0 0 40 0 0 20 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 10 0 0 10 0 10 0 30 10 0 % Q
% Arg: 0 0 10 10 0 0 0 20 0 40 0 30 30 0 60 % R
% Ser: 20 40 0 0 40 0 0 20 20 0 0 10 0 0 10 % S
% Thr: 0 0 10 0 0 0 0 0 0 10 10 0 0 10 0 % T
% Val: 0 0 0 0 0 0 10 10 0 10 20 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _