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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1E
All Species:
0
Human Site:
S358
Identified Species:
0
UniProt:
Q9GZS1
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9GZS1
NP_071935.1
481
53962
S358
H
R
V
V
K
R
K
S
A
L
G
P
G
V
P
Chimpanzee
Pan troglodytes
XP_001169764
477
53423
G357
V
K
R
K
S
A
L
G
P
G
V
P
H
I
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531998
419
47056
G299
V
K
R
K
S
A
L
G
P
G
I
P
H
V
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8K202
482
54015
R359
Q
K
V
I
K
G
K
R
A
L
G
P
G
I
P
Rat
Rattus norvegicus
NP_001101408
434
48751
G314
I
K
G
K
S
A
L
G
P
G
I
P
H
I
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517086
183
20540
L63
L
V
A
E
T
D
R
L
S
Y
M
G
S
N
F
Chicken
Gallus gallus
XP_424416
341
38462
G221
T
G
K
L
D
P
M
G
P
E
C
P
H
I
I
Frog
Xenopus laevis
Q6GLI9
419
47348
L299
T
V
K
R
K
D
I
L
T
P
E
C
P
S
V
Zebra Danio
Brachydanio rerio
NP_001018540
413
46491
G293
F
K
F
G
S
D
D
G
C
P
R
I
I
I
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793654
285
32322
A165
T
E
A
L
E
T
S
A
A
K
A
L
T
H
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
N.A.
75
N.A.
53.3
67.1
N.A.
25.9
38.8
46.5
37.2
N.A.
N.A.
N.A.
N.A.
25.1
Protein Similarity:
100
98.9
N.A.
81.6
N.A.
67.2
79.2
N.A.
32.2
54.2
63.6
59.6
N.A.
N.A.
N.A.
N.A.
37.8
P-Site Identity:
100
6.6
N.A.
13.3
N.A.
60
6.6
N.A.
0
6.6
6.6
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
20
N.A.
20
N.A.
80
20
N.A.
13.3
20
6.6
13.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
20
0
0
30
0
10
30
0
10
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
10
10
0
0
0
% C
% Asp:
0
0
0
0
10
30
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
0
10
10
0
0
0
0
10
10
0
0
0
0
% E
% Phe:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
10
10
10
0
10
0
50
0
30
20
10
20
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
40
10
0
% H
% Ile:
10
0
0
10
0
0
10
0
0
0
20
10
10
50
40
% I
% Lys:
0
50
20
30
30
0
20
0
0
10
0
0
0
0
0
% K
% Leu:
10
0
0
20
0
0
30
20
0
20
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% N
% Pro:
0
0
0
0
0
10
0
0
40
20
0
60
10
0
20
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
20
10
0
10
10
10
0
0
10
0
0
0
0
% R
% Ser:
0
0
0
0
40
0
10
10
10
0
0
0
10
10
0
% S
% Thr:
30
0
0
0
10
10
0
0
10
0
0
0
10
0
0
% T
% Val:
20
20
20
10
0
0
0
0
0
0
10
0
0
20
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _