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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1E
All Species:
4.55
Human Site:
S442
Identified Species:
11.11
UniProt:
Q9GZS1
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.56
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9GZS1
NP_071935.1
481
53962
S442
K
A
M
R
L
K
I
S
K
R
R
V
S
V
A
Chimpanzee
Pan troglodytes
XP_001169764
477
53423
K439
A
M
R
L
K
I
S
K
R
R
V
S
V
A
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531998
419
47056
K381
A
M
R
L
K
I
S
K
R
K
V
S
L
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8K202
482
54015
S443
K
A
M
R
L
K
I
S
K
Q
K
V
S
L
A
Rat
Rattus norvegicus
NP_001101408
434
48751
K396
A
M
R
L
K
I
S
K
R
K
V
S
L
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517086
183
20540
R145
F
G
T
T
K
Q
K
R
A
L
N
A
R
R
M
Chicken
Gallus gallus
XP_424416
341
38462
K303
A
M
R
L
K
V
S
K
A
K
G
M
P
G
L
Frog
Xenopus laevis
Q6GLI9
419
47348
K381
K
V
M
G
L
K
I
K
K
R
M
M
Y
S
E
Zebra Danio
Brachydanio rerio
NP_001018540
413
46491
N375
G
L
T
L
S
R
Q
N
A
L
G
K
E
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793654
285
32322
D247
K
F
P
Q
Y
V
L
D
H
L
P
A
L
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
N.A.
75
N.A.
53.3
67.1
N.A.
25.9
38.8
46.5
37.2
N.A.
N.A.
N.A.
N.A.
25.1
Protein Similarity:
100
98.9
N.A.
81.6
N.A.
67.2
79.2
N.A.
32.2
54.2
63.6
59.6
N.A.
N.A.
N.A.
N.A.
37.8
P-Site Identity:
100
13.3
N.A.
6.6
N.A.
80
0
N.A.
0
0
46.6
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
20
N.A.
20
N.A.
100
13.3
N.A.
6.6
13.3
53.3
13.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
20
0
0
0
0
0
0
30
0
0
20
0
30
40
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% E
% Phe:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
0
10
0
0
0
0
0
0
20
0
0
20
10
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
30
30
0
0
0
0
0
0
0
0
% I
% Lys:
40
0
0
0
50
30
10
50
30
30
10
10
0
0
0
% K
% Leu:
0
10
0
50
30
0
10
0
0
30
0
0
30
10
10
% L
% Met:
0
40
30
0
0
0
0
0
0
0
10
20
0
0
10
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
0
0
0
0
10
0
10
0
0
% P
% Gln:
0
0
0
10
0
10
10
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
40
20
0
10
0
10
30
30
10
0
10
10
10
% R
% Ser:
0
0
0
0
10
0
40
20
0
0
0
30
20
20
0
% S
% Thr:
0
0
20
10
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
10
0
0
0
20
0
0
0
0
30
20
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _