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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1E
All Species:
4.24
Human Site:
T417
Identified Species:
10.37
UniProt:
Q9GZS1
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9GZS1
NP_071935.1
481
53962
T417
H
D
F
Q
I
D
L
T
V
L
Q
R
D
L
K
Chimpanzee
Pan troglodytes
XP_001169764
477
53423
L415
F
Q
I
D
L
T
M
L
Q
R
D
L
K
L
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_531998
419
47056
L357
F
Q
I
D
L
T
M
L
Q
R
D
L
K
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8K202
482
54015
T418
N
N
F
Q
V
D
L
T
A
L
Q
K
D
L
K
Rat
Rattus norvegicus
NP_001101408
434
48751
L372
F
Q
I
D
L
T
V
L
Q
R
D
L
K
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517086
183
20540
E121
N
E
S
E
A
A
S
E
N
Q
A
K
T
Y
R
Chicken
Gallus gallus
XP_424416
341
38462
L279
F
Q
T
D
L
T
V
L
Q
N
D
L
K
L
H
Frog
Xenopus laevis
Q6GLI9
419
47348
L357
D
F
Q
V
D
L
T
L
L
Q
R
D
M
K
L
Zebra Danio
Brachydanio rerio
NP_001018540
413
46491
R351
A
N
L
T
L
L
H
R
D
M
S
I
S
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793654
285
32322
E223
A
L
Q
V
Q
T
E
E
L
L
L
G
V
K
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
N.A.
75
N.A.
53.3
67.1
N.A.
25.9
38.8
46.5
37.2
N.A.
N.A.
N.A.
N.A.
25.1
Protein Similarity:
100
98.9
N.A.
81.6
N.A.
67.2
79.2
N.A.
32.2
54.2
63.6
59.6
N.A.
N.A.
N.A.
N.A.
37.8
P-Site Identity:
100
6.6
N.A.
6.6
N.A.
66.6
6.6
N.A.
0
6.6
0
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
20
N.A.
20
N.A.
93.3
20
N.A.
33.3
20
13.3
20
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
0
0
10
10
0
0
10
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
40
10
20
0
0
10
0
40
10
20
0
0
% D
% Glu:
0
10
0
10
0
0
10
20
0
0
0
0
0
10
0
% E
% Phe:
40
10
20
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% G
% His:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
30
0
10
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
20
40
20
20
% K
% Leu:
0
10
10
0
50
20
20
50
20
30
10
40
0
60
10
% L
% Met:
0
0
0
0
0
0
20
0
0
10
0
0
10
0
0
% M
% Asn:
20
20
0
0
0
0
0
0
10
10
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
40
20
20
10
0
0
0
40
20
20
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
30
10
10
0
0
10
% R
% Ser:
0
0
10
0
0
0
10
0
0
0
10
0
10
0
30
% S
% Thr:
0
0
10
10
0
50
10
20
0
0
0
0
10
0
10
% T
% Val:
0
0
0
20
10
0
20
0
10
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _