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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WNT10A
All Species:
10.91
Human Site:
T280
Identified Species:
20
UniProt:
Q9GZT5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9GZT5
NP_079492.2
417
46444
T280
L
K
T
C
W
Q
V
T
P
E
F
R
T
V
G
Chimpanzee
Pan troglodytes
Q2QLE7
360
40426
M224
L
R
T
C
W
L
A
M
A
D
F
R
K
T
G
Rhesus Macaque
Macaca mulatta
XP_001104947
389
42934
K244
Q
V
V
I
E
N
L
K
R
K
C
K
C
H
G
Dog
Lupus familis
XP_545648
417
46144
T280
L
K
T
C
W
Q
V
T
P
E
F
R
A
V
G
Cat
Felis silvestris
Mouse
Mus musculus
P70701
417
46436
T280
L
K
T
C
W
Q
V
T
P
E
F
R
T
V
G
Rat
Rattus norvegicus
Q9QXQ5
351
39025
T219
S
G
S
C
E
V
K
T
C
W
R
A
V
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Q07DZ8
361
40096
R219
V
S
G
S
C
T
L
R
T
C
W
L
A
M
A
Chicken
Gallus gallus
Q98SN7
385
42934
C240
C
H
G
V
S
G
S
C
T
L
R
T
C
W
L
Frog
Xenopus laevis
P87387
351
40101
M215
L
R
T
C
W
R
A
M
S
D
F
R
K
T
G
Zebra Danio
Brachydanio rerio
P43446
442
50029
S305
K
C
H
G
T
S
G
S
C
Q
L
K
T
C
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609109
432
48310
A245
L
K
T
C
W
K
S
A
P
D
F
H
I
V
G
Honey Bee
Apis mellifera
XP_396944
378
42015
A227
L
K
T
C
W
K
V
A
P
D
F
R
I
V
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781564
350
39795
E219
M
Q
T
P
H
F
R
E
V
G
N
R
L
M
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
36.2
59.9
97.1
N.A.
95.1
39.3
N.A.
37.6
38.1
39.5
67.4
N.A.
41.4
43.1
N.A.
44.1
Protein Similarity:
100
52.5
72.1
97.8
N.A.
96.6
53.7
N.A.
52.5
52.5
53.2
78.9
N.A.
59.2
58.9
N.A.
57.7
P-Site Identity:
100
46.6
6.6
93.3
N.A.
100
13.3
N.A.
0
0
46.6
6.6
N.A.
60
73.3
N.A.
13.3
P-Site Similarity:
100
60
26.6
93.3
N.A.
100
20
N.A.
26.6
0
66.6
26.6
N.A.
73.3
86.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
16
16
8
0
0
8
16
0
8
% A
% Cys:
8
8
0
62
8
0
0
8
16
8
8
0
16
8
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
31
0
0
0
0
0
% D
% Glu:
0
0
0
0
16
0
0
8
0
24
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
54
0
0
0
0
% F
% Gly:
0
8
16
8
0
8
8
0
0
8
0
0
0
0
62
% G
% His:
0
8
8
0
8
0
0
0
0
0
0
8
0
8
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
0
16
0
0
% I
% Lys:
8
39
0
0
0
16
8
8
0
8
0
16
16
0
0
% K
% Leu:
54
0
0
0
0
8
16
0
0
8
8
8
8
0
8
% L
% Met:
8
0
0
0
0
0
0
16
0
0
0
0
0
16
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
39
0
0
0
0
8
8
% P
% Gln:
8
8
0
0
0
24
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
16
0
0
0
8
8
8
8
0
16
54
0
0
0
% R
% Ser:
8
8
8
8
8
8
16
8
8
0
0
0
0
0
0
% S
% Thr:
0
0
62
0
8
8
0
31
16
0
0
8
24
16
0
% T
% Val:
8
8
8
8
0
8
31
0
8
0
0
0
8
39
0
% V
% Trp:
0
0
0
0
54
0
0
0
0
8
8
0
0
8
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _