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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EGLN1 All Species: 24.85
Human Site: S245 Identified Species: 54.67
UniProt: Q9GZT9 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZT9 NP_071334.1 426 46021 S245 G Q L V S Q K S D S S K D I R
Chimpanzee Pan troglodytes XP_525092 422 45794 S241 G Q L V S Q K S D S S K D I R
Rhesus Macaque Macaca mulatta XP_001104870 426 46004 S245 G Q L V S Q K S D S S K D I R
Dog Lupus familis XP_546089 449 47583 S268 G Q L V S Q K S D S S K D I R
Cat Felis silvestris
Mouse Mus musculus Q91YE3 400 43092 S222 G Q L V S Q K S D S S K D I R
Rat Rattus norvegicus P59722 222 24956 T56 D I R G D K I T W I E G K E P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521388 402 44349 D227 C I Y Y L N K D W D A K V S G
Chicken Gallus gallus XP_421233 404 44401 G230 Q L A G P S R G V A K R H L R
Frog Xenopus laevis NP_001086560 408 45308 S227 G Q L V S Q K S D S T R D I R
Zebra Danio Brachydanio rerio NP_001002595 335 37829 T169 D I R G D K I T W V E G K E P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_397368 519 58882 T314 A G A N D L K T I R G D Q I T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.4 97.6 68.5 N.A. 79.1 50.7 N.A. 24.4 39.9 60.5 58.4 N.A. N.A. 37.9 N.A. N.A.
Protein Similarity: 100 79.5 97.6 73.9 N.A. 82.1 51.8 N.A. 35.6 52.3 70.6 65.4 N.A. N.A. 52.4 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 0 N.A. 13.3 6.6 86.6 0 N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 13.3 N.A. 20 33.3 100 13.3 N.A. N.A. 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 19 0 0 0 0 0 0 10 10 0 0 0 0 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 19 0 0 0 28 0 0 10 55 10 0 10 55 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 19 0 0 19 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 55 10 0 28 0 0 0 10 0 0 10 19 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % H
% Ile: 0 28 0 0 0 0 19 0 10 10 0 0 0 64 0 % I
% Lys: 0 0 0 0 0 19 73 0 0 0 10 55 19 0 0 % K
% Leu: 0 10 55 0 10 10 0 0 0 0 0 0 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 19 % P
% Gln: 10 55 0 0 0 55 0 0 0 0 0 0 10 0 0 % Q
% Arg: 0 0 19 0 0 0 10 0 0 10 0 19 0 0 64 % R
% Ser: 0 0 0 0 55 10 0 55 0 55 46 0 0 10 0 % S
% Thr: 0 0 0 0 0 0 0 28 0 0 10 0 0 0 10 % T
% Val: 0 0 0 55 0 0 0 0 10 10 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 28 0 0 0 0 0 0 % W
% Tyr: 0 0 10 10 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _