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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MCOLN1 All Species: 26.06
Human Site: Y169 Identified Species: 63.7
UniProt: Q9GZU1 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZU1 NP_065394.1 580 65022 Y169 G L A L C Q R Y Y H R G H V D
Chimpanzee Pan troglodytes XP_001152356 580 64990 Y169 G L A L C Q R Y Y H R G H V D
Rhesus Macaque Macaca mulatta XP_001089857 580 65086 Y169 G L A L C Q R Y Y H R G H V D
Dog Lupus familis XP_854284 577 64733 Y166 A L A L C Q Q Y Y H R G H V D
Cat Felis silvestris
Mouse Mus musculus Q99J21 580 65487 Y169 A L A L C Q R Y Y H R G H V D
Rat Rattus norvegicus NP_001099373 580 65461 Y169 A L A L C Q R Y Y H R G H V D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520737 451 50656 L51 E E D L R R R L K Y F F M S P
Chicken Gallus gallus XP_423829 489 56157 Y88 A L M L C Q Q Y Y R R G R I D
Frog Xenopus laevis NP_001085687 566 64862 S163 H L N Q S A L S V C Q Q Y Y R
Zebra Danio Brachydanio rerio XP_001336199 565 63585 A161 Q T S V G R Y A Y V P G V G P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 98.4 94.4 N.A. 91.3 91.9 N.A. 62.9 60.5 62.4 58.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 100 98.7 96.5 N.A. 94.4 95 N.A. 68.7 70.8 76.3 73.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 86.6 N.A. 93.3 93.3 N.A. 13.3 60 6.6 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 26.6 73.3 20 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 40 0 60 0 0 10 0 10 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 70 0 0 0 0 10 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 70 % D
% Glu: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 10 10 0 0 0 % F
% Gly: 30 0 0 0 10 0 0 0 0 0 0 80 0 10 0 % G
% His: 10 0 0 0 0 0 0 0 0 60 0 0 60 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % I
% Lys: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % K
% Leu: 0 80 0 80 0 0 10 10 0 0 0 0 0 0 0 % L
% Met: 0 0 10 0 0 0 0 0 0 0 0 0 10 0 0 % M
% Asn: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 20 % P
% Gln: 10 0 0 10 0 70 20 0 0 0 10 10 0 0 0 % Q
% Arg: 0 0 0 0 10 20 60 0 0 10 70 0 10 0 10 % R
% Ser: 0 0 10 0 10 0 0 10 0 0 0 0 0 10 0 % S
% Thr: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 10 0 0 0 0 10 10 0 0 10 60 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 70 80 10 0 0 10 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _