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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM192A
All Species:
32.28
Human Site:
T249
Identified Species:
59.19
UniProt:
Q9GZU8
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9GZU8
NP_079222.1
254
28912
T249
S
S
I
F
R
T
N
T
F
L
E
A
P
_
_
Chimpanzee
Pan troglodytes
XP_001143418
254
28890
T249
S
S
I
F
R
T
N
T
F
L
E
A
P
_
_
Rhesus Macaque
Macaca mulatta
XP_001097573
310
34724
T305
S
S
I
F
R
T
N
T
F
L
E
A
P
_
_
Dog
Lupus familis
XP_535288
254
28596
T249
S
S
I
F
R
T
N
T
F
L
E
A
P
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q91WE2
254
28683
T249
S
S
I
F
R
T
N
T
F
L
E
A
P
_
_
Rat
Rattus norvegicus
NP_001014036
254
28557
T249
S
S
I
F
R
T
N
T
F
L
E
A
P
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508009
219
25628
M213
A
A
L
L
L
I
A
M
P
A
E
S
P
E
_
Chicken
Gallus gallus
XP_414013
255
28682
S250
S
S
V
F
R
S
N
S
F
F
D
G
P
_
_
Frog
Xenopus laevis
NP_001080583
253
28594
T248
S
S
V
F
R
S
G
T
Y
L
D
A
P
_
_
Zebra Danio
Brachydanio rerio
NP_956218
231
26052
S223
A
Y
S
G
S
S
D
S
E
S
S
S
D
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611231
249
28358
K244
C
G
R
K
I
P
K
K
K
Q
C
S
E
_
_
Honey Bee
Apis mellifera
XP_001121863
226
26142
K218
D
L
L
G
R
K
I
K
I
L
K
D
K
E
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001178625
211
24694
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
81.2
94
N.A.
92.9
92.9
N.A.
63.7
77.6
66.5
58.2
N.A.
38.5
39.7
N.A.
34.2
Protein Similarity:
100
99.6
81.9
96.4
N.A.
95.6
96.4
N.A.
72.4
89
83.8
70
N.A.
57
55.9
N.A.
51.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
14.2
53.8
61.5
0
N.A.
0
13.3
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
42.8
84.6
92.3
33.3
N.A.
7.6
26.6
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
0
0
0
0
8
0
0
8
0
54
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
8
0
0
0
16
8
8
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
8
0
54
0
8
16
8
% E
% Phe:
0
0
0
62
0
0
0
0
54
8
0
0
0
0
0
% F
% Gly:
0
8
0
16
0
0
8
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
47
0
8
8
8
0
8
0
0
0
0
0
0
% I
% Lys:
0
0
0
8
0
8
8
16
8
0
8
0
8
0
8
% K
% Leu:
0
8
16
8
8
0
0
0
0
62
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
54
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
0
8
0
0
0
70
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
0
8
0
70
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
62
62
8
0
8
24
0
16
0
8
8
24
0
0
0
% S
% Thr:
0
0
0
0
0
47
0
54
0
0
0
0
0
0
0
% T
% Val:
0
0
16
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
70
77
% _