KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF5A2
All Species:
11.21
Human Site:
T8
Identified Species:
18.97
UniProt:
Q9GZV4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.62
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9GZV4
NP_065123.1
153
16793
T8
M
A
D
E
I
D
F
T
T
G
D
A
G
A
S
Chimpanzee
Pan troglodytes
XP_001174773
286
30517
E140
M
A
D
D
L
D
F
E
T
G
D
A
G
A
S
Rhesus Macaque
Macaca mulatta
XP_001118011
190
21255
E44
M
A
D
D
L
D
F
E
T
G
D
A
G
A
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
XP_001472697
357
39965
E8
M
A
D
D
L
D
F
E
T
G
D
A
G
P
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q07460
153
16702
T8
M
A
D
E
L
D
F
T
T
G
D
A
G
A
S
Frog
Xenopus laevis
NP_001080536
154
16686
T8
M
A
D
D
I
D
F
T
S
G
D
A
G
A
S
Zebra Danio
Brachydanio rerio
NP_998350
155
16861
A9
A
D
P
D
L
D
F
A
S
G
D
A
G
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9GU68
159
17573
E9
A
E
L
D
D
Q
F
E
T
T
D
S
G
A
S
Honey Bee
Apis mellifera
XP_624951
160
17574
E10
D
I
E
D
T
H
F
E
T
G
D
S
G
A
S
Nematode Worm
Caenorhab. elegans
Q20751
161
17935
H12
H
H
D
D
E
H
F
H
T
G
D
S
G
A
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P80639
160
17478
S11
S
E
E
H
H
F
E
S
K
A
D
A
G
A
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XI91
158
17342
E9
S
D
E
E
H
H
F
E
S
S
D
A
G
A
S
Baker's Yeast
Sacchar. cerevisiae
P23301
157
17096
E9
S
D
E
E
H
T
F
E
T
A
D
A
G
S
S
Red Bread Mold
Neurospora crassa
P38672
163
18017
D15
A
Q
H
E
H
T
F
D
S
V
D
A
G
A
S
Conservation
Percent
Protein Identity:
100
45
66.8
N.A.
N.A.
33.8
N.A.
N.A.
N.A.
92.1
79.8
77.4
N.A.
65.4
67.5
59.6
N.A.
Protein Similarity:
100
50
75.2
N.A.
N.A.
40
N.A.
N.A.
N.A.
96.7
91.5
90.3
N.A.
81.7
78.1
73.2
N.A.
P-Site Identity:
100
80
80
N.A.
N.A.
73.3
N.A.
N.A.
N.A.
93.3
86.6
53.3
N.A.
40
46.6
46.6
N.A.
P-Site Similarity:
100
93.3
93.3
N.A.
N.A.
86.6
N.A.
N.A.
N.A.
100
100
73.3
N.A.
53.3
66.6
66.6
N.A.
Percent
Protein Identity:
N.A.
54.3
N.A.
57.5
61.7
60.7
Protein Similarity:
N.A.
70.6
N.A.
73.4
79.6
71.1
P-Site Identity:
N.A.
33.3
N.A.
46.6
46.6
46.6
P-Site Similarity:
N.A.
46.6
N.A.
60
60
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
43
0
0
0
0
0
8
0
15
0
79
0
86
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
22
50
58
8
50
0
8
0
0
100
0
0
0
0
% D
% Glu:
0
15
29
36
8
0
8
50
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
93
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
65
0
0
100
0
0
% G
% His:
8
8
8
8
29
22
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
15
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% K
% Leu:
0
0
8
0
36
0
0
0
0
0
0
0
0
0
0
% L
% Met:
43
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
22
0
0
0
0
0
0
8
29
8
0
22
0
8
93
% S
% Thr:
0
0
0
0
8
15
0
22
65
8
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _