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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF5A2
All Species:
31.21
Human Site:
Y89
Identified Species:
52.82
UniProt:
Q9GZV4
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9GZV4
NP_065123.1
153
16793
Y89
P
N
I
K
R
N
D
Y
Q
L
I
C
I
Q
D
Chimpanzee
Pan troglodytes
XP_001174773
286
30517
F221
P
N
I
K
R
N
D
F
Q
L
I
G
I
Q
D
Rhesus Macaque
Macaca mulatta
XP_001118011
190
21255
F125
P
N
I
K
R
N
D
F
Q
L
I
G
I
Q
D
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
XP_001472697
357
39965
F89
P
N
I
K
R
N
N
F
Q
L
V
G
I
Q
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q07460
153
16702
Y89
P
N
I
K
R
N
D
Y
Q
L
I
G
I
Q
D
Frog
Xenopus laevis
NP_001080536
154
16686
Y89
P
N
I
K
R
C
D
Y
Q
L
I
G
I
I
D
Zebra Danio
Brachydanio rerio
NP_998350
155
16861
Y90
P
N
I
K
R
N
D
Y
Q
L
V
D
I
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9GU68
159
17573
L90
P
N
V
K
R
E
D
L
Q
L
I
A
I
S
D
Honey Bee
Apis mellifera
XP_624951
160
17574
Y91
P
F
V
K
R
E
D
Y
Q
L
A
D
I
S
D
Nematode Worm
Caenorhab. elegans
Q20751
161
17935
Y93
P
V
V
K
R
R
E
Y
L
L
M
A
I
D
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P80639
160
17478
Y92
P
H
V
N
R
T
E
Y
Q
L
I
D
I
S
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XI91
158
17342
Y90
P
H
V
N
R
T
D
Y
Q
L
I
D
I
S
E
Baker's Yeast
Sacchar. cerevisiae
P23301
157
17096
Y90
P
V
V
K
R
N
E
Y
Q
L
L
D
I
D
D
Red Bread Mold
Neurospora crassa
P38672
163
18017
Y96
P
N
V
K
R
T
D
Y
Q
F
S
Y
I
D
E
Conservation
Percent
Protein Identity:
100
45
66.8
N.A.
N.A.
33.8
N.A.
N.A.
N.A.
92.1
79.8
77.4
N.A.
65.4
67.5
59.6
N.A.
Protein Similarity:
100
50
75.2
N.A.
N.A.
40
N.A.
N.A.
N.A.
96.7
91.5
90.3
N.A.
81.7
78.1
73.2
N.A.
P-Site Identity:
100
86.6
86.6
N.A.
N.A.
66.6
N.A.
N.A.
N.A.
93.3
80
73.3
N.A.
66.6
60
46.6
N.A.
P-Site Similarity:
100
93.3
93.3
N.A.
N.A.
93.3
N.A.
N.A.
N.A.
93.3
80
86.6
N.A.
73.3
66.6
66.6
N.A.
Percent
Protein Identity:
N.A.
54.3
N.A.
57.5
61.7
60.7
Protein Similarity:
N.A.
70.6
N.A.
73.4
79.6
71.1
P-Site Identity:
N.A.
46.6
N.A.
53.3
60
53.3
P-Site Similarity:
N.A.
73.3
N.A.
73.3
80
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
8
15
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
0
0
72
0
0
0
0
36
0
22
65
% D
% Glu:
0
0
0
0
0
15
22
0
0
0
0
0
0
0
29
% E
% Phe:
0
8
0
0
0
0
0
22
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
36
0
0
0
% G
% His:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
50
0
0
0
0
0
0
0
58
0
100
8
0
% I
% Lys:
0
0
0
86
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
8
8
93
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
65
0
15
0
50
8
0
0
0
0
0
0
0
8
% N
% Pro:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
93
0
0
0
0
36
0
% Q
% Arg:
0
0
0
0
100
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
8
0
0
36
0
% S
% Thr:
0
0
0
0
0
22
0
0
0
0
0
0
0
0
0
% T
% Val:
0
15
50
0
0
0
0
0
0
0
15
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
72
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _