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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WWTR1 All Species: 10.61
Human Site: S388 Identified Species: 25.93
UniProt: Q9GZV5 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZV5 NP_056287.1 400 44101 S388 P L F N D V E S A L N K S E P
Chimpanzee Pan troglodytes XP_508718 450 48256 L420 G E E L M P S L Q E A L S S D
Rhesus Macaque Macaca mulatta XP_001096954 125 14040 E114 G P L P A V R E Q A M T Q N E
Dog Lupus familis XP_852547 400 43954 S388 P L F N D V E S A L N K S E P
Cat Felis silvestris
Mouse Mus musculus Q9EPK5 395 43601 S383 P L F N D V E S A L N K S E P
Rat Rattus norvegicus Q2EJA0 469 50483 L440 G E E L M P S L Q E A L S S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508758 191 21001 Q180 Q R S M T I S Q P N L E C E G
Chicken Gallus gallus P46936 448 47804 L418 G E E L M P S L Q E A L S S D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_391844 511 54750 S476 G E K N D E L S K P W K S S V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789542 531 58411 D489 M D T M D P S D S G T A V T S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 48.6 20 96.5 N.A. 90.7 47.3 N.A. 43.2 48.4 N.A. N.A. N.A. N.A. 26.4 N.A. 30.8
Protein Similarity: 100 63.3 27 97 N.A. 94.7 61.1 N.A. 45.2 64 N.A. N.A. N.A. N.A. 40.1 N.A. 43.8
P-Site Identity: 100 6.6 6.6 100 N.A. 100 6.6 N.A. 6.6 6.6 N.A. N.A. N.A. N.A. 33.3 N.A. 6.6
P-Site Similarity: 100 6.6 6.6 100 N.A. 100 6.6 N.A. 20 6.6 N.A. N.A. N.A. N.A. 33.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 0 0 30 10 30 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % C
% Asp: 0 10 0 0 50 0 0 10 0 0 0 0 0 0 20 % D
% Glu: 0 40 30 0 0 10 30 10 0 30 0 10 0 40 20 % E
% Phe: 0 0 30 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 50 0 0 0 0 0 0 0 0 10 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 10 0 0 0 0 0 10 0 0 40 0 0 0 % K
% Leu: 0 30 10 30 0 0 10 30 0 30 10 30 0 0 0 % L
% Met: 10 0 0 20 30 0 0 0 0 0 10 0 0 0 0 % M
% Asn: 0 0 0 40 0 0 0 0 0 10 30 0 0 10 0 % N
% Pro: 30 10 0 10 0 40 0 0 10 10 0 0 0 0 30 % P
% Gln: 10 0 0 0 0 0 0 10 40 0 0 0 10 0 0 % Q
% Arg: 0 10 0 0 0 0 10 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 10 0 0 0 50 40 10 0 0 0 70 40 10 % S
% Thr: 0 0 10 0 10 0 0 0 0 0 10 10 0 10 0 % T
% Val: 0 0 0 0 0 40 0 0 0 0 0 0 10 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _