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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WWTR1
All Species:
14.85
Human Site:
T346
Identified Species:
36.3
UniProt:
Q9GZV5
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9GZV5
NP_056287.1
400
44101
T346
T
G
E
N
A
G
Q
T
P
M
N
I
N
P
Q
Chimpanzee
Pan troglodytes
XP_508718
450
48256
S378
T
G
D
T
I
N
Q
S
T
L
P
S
Q
Q
N
Rhesus Macaque
Macaca mulatta
XP_001096954
125
14040
I72
E
R
Y
F
L
N
H
I
D
Q
T
T
W
Q
D
Dog
Lupus familis
XP_852547
400
43954
T346
T
G
E
N
A
G
Q
T
P
M
N
I
N
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9EPK5
395
43601
T341
T
G
E
N
S
G
Q
T
P
M
T
V
N
P
Q
Rat
Rattus norvegicus
Q2EJA0
469
50483
S398
T
G
D
T
I
S
Q
S
T
L
P
S
Q
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508758
191
21001
N138
T
G
Q
R
Y
F
L
N
H
I
E
K
I
T
T
Chicken
Gallus gallus
P46936
448
47804
S376
T
G
D
S
I
S
Q
S
N
I
P
S
H
Q
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_391844
511
54750
D434
D
N
I
D
S
T
D
D
L
V
P
S
L
Q
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789542
531
58411
D447
S
S
E
A
P
P
T
D
R
K
P
L
D
K
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.6
20
96.5
N.A.
90.7
47.3
N.A.
43.2
48.4
N.A.
N.A.
N.A.
N.A.
26.4
N.A.
30.8
Protein Similarity:
100
63.3
27
97
N.A.
94.7
61.1
N.A.
45.2
64
N.A.
N.A.
N.A.
N.A.
40.1
N.A.
43.8
P-Site Identity:
100
20
0
100
N.A.
80
20
N.A.
13.3
20
N.A.
N.A.
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
100
40
0
100
N.A.
93.3
40
N.A.
26.6
53.3
N.A.
N.A.
N.A.
N.A.
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
20
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
30
10
0
0
10
20
10
0
0
0
10
0
10
% D
% Glu:
10
0
40
0
0
0
0
0
0
0
10
0
0
0
0
% E
% Phe:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
70
0
0
0
30
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
10
0
10
0
0
0
10
0
0
% H
% Ile:
0
0
10
0
30
0
0
10
0
20
0
20
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
10
0
10
0
10
0
% K
% Leu:
0
0
0
0
10
0
10
0
10
20
0
10
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
30
0
0
0
0
0
% M
% Asn:
0
10
0
30
0
20
0
10
10
0
20
0
30
0
20
% N
% Pro:
0
0
0
0
10
10
0
0
30
0
50
0
0
30
0
% P
% Gln:
0
0
10
0
0
0
60
0
0
10
0
0
20
50
40
% Q
% Arg:
0
10
0
10
0
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
10
10
0
10
20
20
0
30
0
0
0
40
0
0
10
% S
% Thr:
70
0
0
20
0
10
10
30
20
0
20
10
0
10
10
% T
% Val:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _