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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRDM14
All Species:
5.15
Human Site:
S125
Identified Species:
11.33
UniProt:
Q9GZV8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9GZV8
NP_078780.1
571
64062
S125
S
H
E
Y
A
G
A
S
S
E
D
L
G
H
Q
Chimpanzee
Pan troglodytes
A2T736
578
65733
R131
T
L
L
E
D
L
E
R
Q
I
D
I
L
G
R
Rhesus Macaque
Macaca mulatta
XP_001082029
571
64054
S125
S
H
E
Y
T
A
A
S
S
E
D
L
G
H
Q
Dog
Lupus familis
XP_544117
571
64407
G125
N
S
S
H
E
Y
R
G
A
T
S
G
D
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q3UZD5
596
64484
A144
D
L
C
L
G
A
S
A
G
P
G
P
A
K
C
Rat
Rattus norvegicus
A1L1L7
553
62987
R125
A
S
Q
Q
E
L
L
R
G
N
I
S
N
G
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510219
198
22613
Chicken
Gallus gallus
Frog
Xenopus laevis
P18753
780
88631
R132
Y
N
E
P
S
K
I
R
A
E
G
G
D
F
C
Zebra Danio
Brachydanio rerio
NP_001157303
517
58298
S92
Y
F
Q
H
I
Q
P
S
Q
S
V
Y
N
A
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_509530
594
67513
P126
Q
Y
E
P
D
T
A
P
P
S
R
S
T
S
P
Sea Urchin
Strong. purpuratus
XP_794184
678
75009
P122
I
S
V
S
P
V
H
P
L
H
H
L
T
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.4
96.6
80.2
N.A.
25.5
21.1
N.A.
27.5
N.A.
20.2
47.4
N.A.
N.A.
N.A.
30.1
37.1
Protein Similarity:
100
38.2
97.9
85.2
N.A.
39.2
37.8
N.A.
29.4
N.A.
33.8
59
N.A.
N.A.
N.A.
43.7
49.5
P-Site Identity:
100
6.6
86.6
0
N.A.
0
0
N.A.
0
N.A.
13.3
6.6
N.A.
N.A.
N.A.
13.3
6.6
P-Site Similarity:
100
26.6
86.6
20
N.A.
13.3
13.3
N.A.
0
N.A.
33.3
26.6
N.A.
N.A.
N.A.
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
19
28
10
19
0
0
0
10
10
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
19
% C
% Asp:
10
0
0
0
19
0
0
0
0
0
28
0
19
0
10
% D
% Glu:
0
0
37
10
19
0
10
0
0
28
0
0
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
0
10
10
0
10
19
0
19
19
19
19
0
% G
% His:
0
19
0
19
0
0
10
0
0
10
10
0
0
19
0
% H
% Ile:
10
0
0
0
10
0
10
0
0
10
10
10
0
0
0
% I
% Lys:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
19
10
10
0
19
10
0
10
0
0
28
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
10
10
0
0
0
0
0
0
0
10
0
0
19
0
0
% N
% Pro:
0
0
0
19
10
0
10
19
10
10
0
10
0
0
19
% P
% Gln:
10
0
19
10
0
10
0
0
19
0
0
0
0
0
19
% Q
% Arg:
0
0
0
0
0
0
10
28
0
0
10
0
0
0
19
% R
% Ser:
19
28
10
10
10
0
10
28
19
19
10
19
0
19
0
% S
% Thr:
10
0
0
0
10
10
0
0
0
10
0
0
19
0
0
% T
% Val:
0
0
10
0
0
10
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
19
10
0
19
0
10
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _