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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRDM14
All Species:
9.39
Human Site:
S246
Identified Species:
20.67
UniProt:
Q9GZV8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9GZV8
NP_078780.1
571
64062
S246
P
Q
T
L
D
K
D
S
L
Q
L
P
E
G
L
Chimpanzee
Pan troglodytes
A2T736
578
65733
F252
R
D
N
R
P
E
D
F
R
N
V
F
S
L
G
Rhesus Macaque
Macaca mulatta
XP_001082029
571
64054
S246
P
Q
T
V
D
K
D
S
L
Q
L
P
E
G
L
Dog
Lupus familis
XP_544117
571
64407
S246
C
R
T
L
D
K
D
S
L
Q
L
P
E
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3UZD5
596
64484
A265
G
L
A
Y
G
I
C
A
A
Q
R
I
Q
Q
G
Rat
Rattus norvegicus
A1L1L7
553
62987
G246
T
H
Q
R
T
H
S
G
D
K
L
Y
E
L
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510219
198
22613
Chicken
Gallus gallus
Frog
Xenopus laevis
P18753
780
88631
S253
G
K
K
P
F
P
C
S
E
C
G
K
C
F
A
Zebra Danio
Brachydanio rerio
NP_001157303
517
58298
V213
N
G
R
L
S
H
F
V
D
G
R
G
A
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_509530
594
67513
I247
I
S
N
T
H
L
L
I
L
C
T
H
K
M
I
Sea Urchin
Strong. purpuratus
XP_794184
678
75009
R243
I
L
R
S
S
L
G
R
M
S
P
H
Y
S
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.4
96.6
80.2
N.A.
25.5
21.1
N.A.
27.5
N.A.
20.2
47.4
N.A.
N.A.
N.A.
30.1
37.1
Protein Similarity:
100
38.2
97.9
85.2
N.A.
39.2
37.8
N.A.
29.4
N.A.
33.8
59
N.A.
N.A.
N.A.
43.7
49.5
P-Site Identity:
100
6.6
93.3
86.6
N.A.
6.6
13.3
N.A.
0
N.A.
6.6
6.6
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
100
20
100
93.3
N.A.
20
20
N.A.
0
N.A.
13.3
6.6
N.A.
N.A.
N.A.
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
10
10
0
0
0
10
0
10
% A
% Cys:
10
0
0
0
0
0
19
0
0
19
0
0
10
0
0
% C
% Asp:
0
10
0
0
28
0
37
0
19
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
10
0
0
10
0
0
0
37
0
0
% E
% Phe:
0
0
0
0
10
0
10
10
0
0
0
10
0
10
0
% F
% Gly:
19
10
0
0
10
0
10
10
0
10
10
10
0
28
28
% G
% His:
0
10
0
0
10
19
0
0
0
0
0
19
0
0
0
% H
% Ile:
19
0
0
0
0
10
0
10
0
0
0
10
0
0
10
% I
% Lys:
0
10
10
0
0
28
0
0
0
10
0
10
10
0
0
% K
% Leu:
0
19
0
28
0
19
10
0
37
0
37
0
0
19
28
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% M
% Asn:
10
0
19
0
0
0
0
0
0
10
0
0
0
0
10
% N
% Pro:
19
0
0
10
10
10
0
0
0
0
10
28
0
10
0
% P
% Gln:
0
19
10
0
0
0
0
0
0
37
0
0
10
10
0
% Q
% Arg:
10
10
19
19
0
0
0
10
10
0
19
0
0
0
0
% R
% Ser:
0
10
0
10
19
0
10
37
0
10
0
0
10
10
0
% S
% Thr:
10
0
28
10
10
0
0
0
0
0
10
0
0
0
0
% T
% Val:
0
0
0
10
0
0
0
10
0
0
10
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
10
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _