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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IL22 All Species: 15.45
Human Site: S108 Identified Species: 68
UniProt: Q9GZX6 Number Species: 5
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZX6 NP_065386.1 179 20011 S108 E E V L F P Q S D R F Q P Y M
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001117159 179 19924 S108 E E V L L P Q S D R F Q P Y M
Dog Lupus familis XP_538274 179 20064 S108 E E V L L P Q S D R F Q P Y M
Cat Felis silvestris
Mouse Mus musculus Q9JJY9 179 20088 S108 E D V L L P Q S D R F Q P Y M
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511218 180 20317 Y109 E V V I P P Q Y T Q L M P F I
Chicken Gallus gallus XP_416079 197 22551 A114 K D V L L T E A K E R Y P Y A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 95.5 90.5 N.A. 78.2 N.A. N.A. 42.2 39.5 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 96.6 94.9 N.A. 88.8 N.A. N.A. 60.5 59.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 93.3 93.3 N.A. 86.6 N.A. N.A. 33.3 26.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 93.3 93.3 N.A. 93.3 N.A. N.A. 60 53.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 17 0 0 0 0 0 0 17 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 34 0 0 0 0 0 0 67 0 0 0 0 0 0 % D
% Glu: 84 50 0 0 0 0 17 0 0 17 0 0 0 0 0 % E
% Phe: 0 0 0 0 17 0 0 0 0 0 67 0 0 17 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 17 0 0 0 0 0 0 0 0 0 0 17 % I
% Lys: 17 0 0 0 0 0 0 0 17 0 0 0 0 0 0 % K
% Leu: 0 0 0 84 67 0 0 0 0 0 17 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 17 0 0 67 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 17 84 0 0 0 0 0 0 100 0 0 % P
% Gln: 0 0 0 0 0 0 84 0 0 17 0 67 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 67 17 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 67 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 17 0 0 17 0 0 0 0 0 0 % T
% Val: 0 17 100 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 17 0 0 0 17 0 84 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _