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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NXF2 All Species: 8.18
Human Site: S93 Identified Species: 20
UniProt: Q9GZY0 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZY0 NP_001093156.1 626 71627 S93 E R R M K W H S E D E I R I T
Chimpanzee Pan troglodytes XP_001134768 626 71505 S93 Q R R T N W H S E D E I R I T
Rhesus Macaque Macaca mulatta XP_001094356 760 86437 S227 D R R M K W H S E D E I C I T
Dog Lupus familis XP_549146 615 70268 G96 I H I T V W K G R K T L K K E
Cat Felis silvestris
Mouse Mus musculus Q99JX7 618 70282 D98 I H I T V R R D R A P A E R G
Rat Rattus norvegicus O88984 618 70343 D98 I H V T V R R D R A P Q E R G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001084975 614 69836 R98 K K F G G F H R D S P H Q G R
Zebra Danio Brachydanio rerio XP_001923961 642 71544 G110 R K G G R G G G G N D D R G G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9U1H9 672 76230 R93 K D R P T S R R R G S P I P R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9XVS7 628 70944 V93 A S I A N T G V R N A D I V Y
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.7 77.8 71.7 N.A. 56.2 56.5 N.A. N.A. N.A. 44.7 44.7 N.A. 27.8 N.A. 25.9 N.A.
Protein Similarity: 100 98.8 79.8 80.9 N.A. 73.3 71.5 N.A. N.A. N.A. 63 62.4 N.A. 46.8 N.A. 45.7 N.A.
P-Site Identity: 100 80 86.6 6.6 N.A. 0 0 N.A. N.A. N.A. 6.6 6.6 N.A. 6.6 N.A. 0 N.A.
P-Site Similarity: 100 86.6 93.3 20 N.A. 0 0 N.A. N.A. N.A. 40 33.3 N.A. 13.3 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 10 0 0 0 0 0 20 10 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % C
% Asp: 10 10 0 0 0 0 0 20 10 30 10 20 0 0 0 % D
% Glu: 10 0 0 0 0 0 0 0 30 0 30 0 20 0 10 % E
% Phe: 0 0 10 0 0 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 20 10 10 20 20 10 10 0 0 0 20 30 % G
% His: 0 30 0 0 0 0 40 0 0 0 0 10 0 0 0 % H
% Ile: 30 0 30 0 0 0 0 0 0 0 0 30 20 30 0 % I
% Lys: 20 20 0 0 20 0 10 0 0 10 0 0 10 10 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % L
% Met: 0 0 0 20 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 20 0 0 0 0 20 0 0 0 0 0 % N
% Pro: 0 0 0 10 0 0 0 0 0 0 30 10 0 10 0 % P
% Gln: 10 0 0 0 0 0 0 0 0 0 0 10 10 0 0 % Q
% Arg: 10 30 40 0 10 20 30 20 50 0 0 0 30 20 20 % R
% Ser: 0 10 0 0 0 10 0 30 0 10 10 0 0 0 0 % S
% Thr: 0 0 0 40 10 10 0 0 0 0 10 0 0 0 30 % T
% Val: 0 0 10 0 30 0 0 10 0 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 40 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _