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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MFF
All Species:
13.64
Human Site:
S258
Identified Species:
30
UniProt:
Q9GZY8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9GZY8
NP_064579.3
342
38465
S258
R
P
V
L
R
G
G
S
A
A
A
T
S
N
P
Chimpanzee
Pan troglodytes
XP_516131
372
41638
S288
R
P
V
L
R
G
G
S
A
A
A
T
S
N
P
Rhesus Macaque
Macaca mulatta
XP_001110642
341
38439
S257
R
P
V
L
R
G
G
S
A
A
A
T
S
N
P
Dog
Lupus familis
XP_850079
342
38482
S258
R
P
V
L
R
G
G
S
A
A
A
T
S
N
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6PCP5
291
32913
I223
H
D
N
V
R
Y
G
I
S
N
L
D
A
A
I
Rat
Rattus norvegicus
Q4KM98
218
24952
I150
R
N
D
S
M
Y
G
I
S
S
L
D
A
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519323
251
27935
R183
H
R
S
D
S
A
P
R
N
K
I
S
R
F
Q
Chicken
Gallus gallus
XP_001233530
330
37495
A246
P
V
L
R
G
G
S
A
A
T
T
S
S
N
P
Frog
Xenopus laevis
Q6DD53
219
24655
M151
R
H
D
S
M
S
A
M
S
T
L
D
T
T
L
Zebra Danio
Brachydanio rerio
Q503U3
275
31342
L207
S
Q
R
G
R
A
S
L
V
T
F
D
A
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198768
213
23716
L144
S
D
P
N
S
S
V
L
L
A
D
N
T
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.5
97.6
95
N.A.
80.1
60.5
N.A.
63.1
81.5
42.4
45.3
N.A.
N.A.
N.A.
N.A.
20.1
Protein Similarity:
100
90.3
98.2
97
N.A.
82.4
62.8
N.A.
67.5
88.8
50.2
61.4
N.A.
N.A.
N.A.
N.A.
34.8
P-Site Identity:
100
100
100
100
N.A.
13.3
13.3
N.A.
0
33.3
6.6
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
33.3
33.3
N.A.
6.6
53.3
20
20
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
19
10
10
46
46
37
0
28
28
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
19
19
10
0
0
0
0
0
0
10
37
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% F
% Gly:
0
0
0
10
10
46
55
0
0
0
0
0
0
0
0
% G
% His:
19
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
19
0
0
10
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% K
% Leu:
0
0
10
37
0
0
0
19
10
0
28
0
0
0
19
% L
% Met:
0
0
0
0
19
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
10
10
10
0
0
0
0
10
10
0
10
0
46
0
% N
% Pro:
10
37
10
0
0
0
10
0
0
0
0
0
0
0
46
% P
% Gln:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
55
10
10
10
55
0
0
10
0
0
0
0
10
0
0
% R
% Ser:
19
0
10
19
19
19
19
37
28
10
0
19
46
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
28
10
37
19
10
0
% T
% Val:
0
10
37
10
0
0
10
0
10
0
0
0
0
0
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
19
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _