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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHRNA10
All Species:
15.15
Human Site:
S294
Identified Species:
25.64
UniProt:
Q9GZZ6
Number Species:
13
Phosphosite Substitution
Charge Score:
0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9GZZ6
NP_065135.2
450
49705
S294
E
S
M
P
P
A
E
S
V
P
L
I
G
K
Y
Chimpanzee
Pan troglodytes
Q5IS76
494
56903
L298
E
T
I
P
S
T
S
L
V
V
P
L
V
G
E
Rhesus Macaque
Macaca mulatta
Q866A2
502
56411
D288
E
I
M
P
A
T
S
D
S
V
P
L
I
A
Q
Dog
Lupus familis
XP_545950
701
79638
N517
E
I
M
P
A
S
E
N
V
P
L
I
G
K
Y
Cat
Felis silvestris
Mouse
Mus musculus
P49582
502
56613
D288
E
I
M
P
A
T
S
D
S
V
P
L
I
A
Q
Rat
Rattus norvegicus
Q9JLB5
447
49801
S294
E
S
M
P
P
A
E
S
V
P
L
I
G
K
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508727
582
66030
N273
E
S
M
P
P
S
E
N
V
P
L
I
G
K
Y
Chicken
Gallus gallus
Q9I8C7
452
50034
S296
E
S
M
P
P
S
E
S
V
P
L
I
G
K
Y
Frog
Xenopus laevis
P05377
457
52088
S289
E
L
I
P
S
T
S
S
A
V
P
L
I
G
K
Zebra Danio
Brachydanio rerio
XP_001920894
457
51985
S276
E
S
M
P
P
S
E
S
V
P
L
I
G
K
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P09478
567
64001
L298
E
I
I
P
P
T
S
L
T
V
P
L
L
G
K
Honey Bee
Apis mellifera
NP_001073564
529
59946
D320
E
T
L
P
Q
V
S
D
A
I
P
L
L
G
S
Nematode Worm
Caenorhab. elegans
Q9N587
502
57373
L317
E
I
I
P
S
T
S
L
V
I
P
L
I
G
K
Sea Urchin
Strong. purpuratus
XP_782644
473
54090
E288
E
T
M
P
P
T
S
E
V
V
P
L
I
A
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34.4
38.4
39
N.A.
38.8
90
N.A.
46.3
65.4
33.7
56.4
N.A.
34.5
35.9
35.4
38
Protein Similarity:
100
52.6
54.5
49.5
N.A.
54.7
92.8
N.A.
57.2
75.8
55.1
71.5
N.A.
50.2
53.6
53.7
57.7
P-Site Identity:
100
20
20
73.3
N.A.
20
100
N.A.
86.6
93.3
20
93.3
N.A.
20
13.3
20
33.3
P-Site Similarity:
100
40
26.6
86.6
N.A.
26.6
100
N.A.
100
100
33.3
100
N.A.
33.3
33.3
33.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
22
15
0
0
15
0
0
0
0
22
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
22
0
0
0
0
0
0
0
% D
% Glu:
100
0
0
0
0
0
43
8
0
0
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
43
36
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
36
29
0
0
0
0
0
0
15
0
43
36
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
43
22
% K
% Leu:
0
8
8
0
0
0
0
22
0
0
43
58
15
0
0
% L
% Met:
0
0
65
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
100
50
0
0
0
0
43
58
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
22
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
36
0
0
22
29
58
36
15
0
0
0
0
0
8
% S
% Thr:
0
22
0
0
0
50
0
0
8
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
8
0
0
65
43
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
43
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _