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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHRNA10
All Species:
7.27
Human Site:
S371
Identified Species:
12.31
UniProt:
Q9GZZ6
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9GZZ6
NP_065135.2
450
49705
S371
E
L
S
P
S
P
Q
S
P
E
G
G
A
G
P
Chimpanzee
Pan troglodytes
Q5IS76
494
56903
K380
G
L
A
R
R
P
A
K
G
K
L
A
S
H
G
Rhesus Macaque
Macaca mulatta
Q866A2
502
56411
E370
R
C
S
L
A
S
V
E
M
S
A
V
A
P
P
Dog
Lupus familis
XP_545950
701
79638
N632
D
L
G
C
H
G
E
N
P
Q
D
A
D
S
Y
Cat
Felis silvestris
Mouse
Mus musculus
P49582
502
56613
E370
R
C
S
L
A
S
V
E
L
S
A
G
A
G
P
Rat
Rattus norvegicus
Q9JLB5
447
49801
P371
E
S
A
P
S
L
Q
P
P
P
A
S
P
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508727
582
66030
E371
E
V
S
G
D
Q
E
E
N
Q
L
V
R
A
K
Chicken
Gallus gallus
Q9I8C7
452
50034
R373
G
T
G
G
M
G
P
R
D
P
P
G
E
G
V
Frog
Xenopus laevis
P05377
457
52088
S372
E
M
D
I
S
H
I
S
G
K
L
G
P
A
A
Zebra Danio
Brachydanio rerio
XP_001920894
457
51985
T341
E
V
G
E
N
C
T
T
P
E
S
D
R
G
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P09478
567
64001
H377
E
V
L
T
D
V
Y
H
L
P
P
D
V
D
K
Honey Bee
Apis mellifera
NP_001073564
529
59946
T388
G
K
K
I
T
K
K
T
I
L
G
G
N
R
R
Nematode Worm
Caenorhab. elegans
Q9N587
502
57373
A394
N
R
K
F
D
S
R
A
S
T
F
S
I
G
V
Sea Urchin
Strong. purpuratus
XP_782644
473
54090
S388
G
I
A
I
M
D
D
S
E
K
K
S
S
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34.4
38.4
39
N.A.
38.8
90
N.A.
46.3
65.4
33.7
56.4
N.A.
34.5
35.9
35.4
38
Protein Similarity:
100
52.6
54.5
49.5
N.A.
54.7
92.8
N.A.
57.2
75.8
55.1
71.5
N.A.
50.2
53.6
53.7
57.7
P-Site Identity:
100
13.3
20
13.3
N.A.
33.3
33.3
N.A.
13.3
13.3
26.6
33.3
N.A.
6.6
13.3
6.6
6.6
P-Site Similarity:
100
33.3
26.6
40
N.A.
40
40
N.A.
33.3
13.3
40
53.3
N.A.
13.3
33.3
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
22
0
15
0
8
8
0
0
22
15
22
22
8
% A
% Cys:
0
15
0
8
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
22
8
8
0
8
0
8
15
8
8
0
% D
% Glu:
43
0
0
8
0
0
15
22
8
15
0
0
8
8
8
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
29
0
22
15
0
15
0
0
15
0
15
36
0
36
15
% G
% His:
0
0
0
0
8
8
0
8
0
0
0
0
0
8
0
% H
% Ile:
0
8
0
22
0
0
8
0
8
0
0
0
8
0
0
% I
% Lys:
0
8
15
0
0
8
8
8
0
22
8
0
0
0
15
% K
% Leu:
0
22
8
15
0
8
0
0
15
8
22
0
0
0
0
% L
% Met:
0
8
0
0
15
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
8
0
0
8
8
0
0
0
8
0
0
% N
% Pro:
0
0
0
15
0
15
8
8
29
22
15
0
15
8
29
% P
% Gln:
0
0
0
0
0
8
15
0
0
15
0
0
0
0
0
% Q
% Arg:
15
8
0
8
8
0
8
8
0
0
0
0
15
8
8
% R
% Ser:
0
8
29
0
22
22
0
22
8
15
8
22
15
8
0
% S
% Thr:
0
8
0
8
8
0
8
15
0
8
0
0
0
0
0
% T
% Val:
0
22
0
0
0
8
15
0
0
0
0
15
8
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _