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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GFRA4 All Species: 27.88
Human Site: Y46 Identified Species: 76.67
UniProt: Q9GZZ7 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZZ7 NP_071422.1 299 31670 Y46 C Q R L R S E Y V A Q C L G R
Chimpanzee Pan troglodytes XP_001168964 212 22417 L11 C L G P A L L L P L L L G S V
Rhesus Macaque Macaca mulatta XP_001111233 268 28598 Y45 C Q R L R S E Y V A Q C L S R
Dog Lupus familis XP_851489 317 34147 Y94 C Q R L R T E Y V A Q C L G R
Cat Felis silvestris
Mouse Mus musculus Q9JJT2 260 27972 Y46 C Q Q L R S E Y V A R C L G R
Rat Rattus norvegicus Q9EPI2 273 29663 Y57 C Q Q L R S E Y V A Q C L G R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513939 304 33762 Y41 C K K Y R S A Y I T P C T S S
Chicken Gallus gallus O93512 431 47946 Y165 C Q R L R T E Y V S F C I R R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_694008 546 59918 Y254 C Q R L R T E Y V S T C I K P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 60.8 78.9 64.3 N.A. 60.5 60.8 N.A. 25.6 26.4 N.A. 20.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 63.2 80.9 69 N.A. 66.2 66.8 N.A. 38.1 38.2 N.A. 30.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 93.3 93.3 N.A. 86.6 93.3 N.A. 33.3 66.6 N.A. 60 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 6.6 93.3 100 N.A. 100 100 N.A. 53.3 86.6 N.A. 80 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 12 0 12 0 0 56 0 0 0 0 0 % A
% Cys: 100 0 0 0 0 0 0 0 0 0 0 89 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 78 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % F
% Gly: 0 0 12 0 0 0 0 0 0 0 0 0 12 45 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 12 0 0 0 23 0 0 % I
% Lys: 0 12 12 0 0 0 0 0 0 0 0 0 0 12 0 % K
% Leu: 0 12 0 78 0 12 12 12 0 12 12 12 56 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 12 0 0 0 0 12 0 12 0 0 0 12 % P
% Gln: 0 78 23 0 0 0 0 0 0 0 45 0 0 0 0 % Q
% Arg: 0 0 56 0 89 0 0 0 0 0 12 0 0 12 67 % R
% Ser: 0 0 0 0 0 56 0 0 0 23 0 0 0 34 12 % S
% Thr: 0 0 0 0 0 34 0 0 0 12 12 0 12 0 0 % T
% Val: 0 0 0 0 0 0 0 0 78 0 0 0 0 0 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 12 0 0 0 89 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _