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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MKRN2
All Species:
13.64
Human Site:
T122
Identified Species:
25
UniProt:
Q9H000
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H000
NP_054879.3
416
46940
T122
S
G
M
A
E
R
K
T
Q
P
S
M
V
S
N
Chimpanzee
Pan troglodytes
XP_516287
414
46535
P122
M
A
E
G
K
T
Q
P
S
M
A
S
N
P
G
Rhesus Macaque
Macaca mulatta
XP_001086204
491
55036
T197
S
G
M
A
E
G
K
T
Q
P
S
M
V
S
N
Dog
Lupus familis
XP_533737
512
57293
T218
S
G
M
A
E
E
K
T
C
P
S
V
V
S
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9ERV1
416
46544
T122
T
G
L
A
E
D
K
T
P
P
S
K
V
N
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Q9TT91
478
52887
G171
N
A
I
E
F
V
P
G
Q
P
Y
C
G
R
A
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989619
417
46464
K122
G
L
N
E
E
K
E
K
A
S
T
T
N
N
V
Frog
Xenopus laevis
B0F0H3
409
45981
C122
D
P
A
L
Q
P
G
C
I
T
E
S
Q
G
S
Zebra Danio
Brachydanio rerio
Q9DFG8
414
46462
N122
S
A
E
S
S
E
L
N
E
C
W
E
Q
R
D
Tiger Blowfish
Takifugu rubipres
NP_001072101
402
44972
T122
T
Y
V
D
A
I
R
T
G
L
S
S
S
S
Q
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121251
415
46952
I125
W
V
K
A
P
E
F
I
P
S
H
I
A
G
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783167
572
64160
F143
E
F
V
P
G
Q
P
F
Q
G
T
L
P
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q6IDS6
323
36544
L62
R
A
A
S
N
L
P
L
S
S
D
S
E
S
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
83
75.5
N.A.
88.2
N.A.
40.7
N.A.
74
63.9
60.5
53.3
N.A.
35
N.A.
29.7
Protein Similarity:
100
99
83.9
77.9
N.A.
94.2
N.A.
55.4
N.A.
81.7
76.4
72.5
66.1
N.A.
52.4
N.A.
42.8
P-Site Identity:
100
0
93.3
80
N.A.
60
N.A.
13.3
N.A.
6.6
0
6.6
20
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
20
93.3
86.6
N.A.
80
N.A.
26.6
N.A.
33.3
13.3
26.6
40
N.A.
20
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
31
16
39
8
0
0
0
8
0
8
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
8
8
8
0
8
0
0
0
% C
% Asp:
8
0
0
8
0
8
0
0
0
0
8
0
0
0
8
% D
% Glu:
8
0
16
16
39
24
8
0
8
0
8
8
8
0
0
% E
% Phe:
0
8
0
0
8
0
8
8
0
0
0
0
0
0
0
% F
% Gly:
8
31
0
8
8
8
8
8
8
8
0
0
8
16
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
8
0
0
8
0
8
8
0
0
8
0
0
0
% I
% Lys:
0
0
8
0
8
8
31
8
0
0
0
8
0
0
0
% K
% Leu:
0
8
8
8
0
8
8
8
0
8
0
8
0
0
8
% L
% Met:
8
0
24
0
0
0
0
0
0
8
0
16
0
0
0
% M
% Asn:
8
0
8
0
8
0
0
8
0
0
0
0
16
16
31
% N
% Pro:
0
8
0
8
8
8
24
8
16
39
0
0
8
16
0
% P
% Gln:
0
0
0
0
8
8
8
0
31
0
0
0
16
0
8
% Q
% Arg:
8
0
0
0
0
8
8
0
0
0
0
0
0
16
0
% R
% Ser:
31
0
0
16
8
0
0
0
16
24
39
31
8
39
24
% S
% Thr:
16
0
0
0
0
8
0
39
0
8
16
8
0
0
0
% T
% Val:
0
8
16
0
0
8
0
0
0
0
0
8
31
0
8
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _