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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LHPP All Species: 4.55
Human Site: Y99 Identified Species: 10
UniProt: Q9H008 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H008 NP_071409 270 29165 Y99 K E Q G L R P Y L L I H D G V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001083060 270 29064 Y99 K E R G L R P Y L L I H D G V
Dog Lupus familis XP_544060 270 29229 H99 K E R G L R P H L L V H D G V
Cat Felis silvestris
Mouse Mus musculus Q9D7I5 270 29126 H99 K E R G L R P H L L I H E G V
Rat Rattus norvegicus Q5I0D5 270 29172 H99 K E R G L R P H L L I H E G V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505830 259 28329 M91 E Q K Q V R P M L L V D D R A
Chicken Gallus gallus XP_424063 266 28508 H97 K E R G L R P H L L V H D D L
Frog Xenopus laevis Q3B8E3 270 29197 H97 K E R G L R P H L L V H N D L
Zebra Danio Brachydanio rerio A5PLK2 270 29606 H101 Q K R H L R P H L L V H D D L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_506040 266 29486 H95 R E N K L R P H L F V R D D V
Sea Urchin Strong. purpuratus XP_001203488 271 29577 L100 A R G L T P H L L V Y P G V L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 97 87 N.A. 88.1 90 N.A. 40.3 69.6 66.3 62.5 N.A. N.A. N.A. 42.2 60.1
Protein Similarity: 100 N.A. 98.5 92.2 N.A. 92.9 93.6 N.A. 60.3 81.4 82.5 77.4 N.A. N.A. N.A. 62.9 76
P-Site Identity: 100 N.A. 93.3 80 N.A. 80 80 N.A. 33.3 66.6 60 46.6 N.A. N.A. N.A. 46.6 6.6
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 66.6 93.3 93.3 86.6 N.A. N.A. N.A. 66.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 10 64 37 0 % D
% Glu: 10 73 0 0 0 0 0 0 0 0 0 0 19 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % F
% Gly: 0 0 10 64 0 0 0 0 0 0 0 0 10 46 0 % G
% His: 0 0 0 10 0 0 10 64 0 0 0 73 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 37 0 0 0 0 % I
% Lys: 64 10 10 10 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 10 82 0 0 10 100 82 0 0 0 0 37 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 0 0 0 0 0 0 0 0 10 0 0 % N
% Pro: 0 0 0 0 0 10 91 0 0 0 0 10 0 0 0 % P
% Gln: 10 10 10 10 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 10 10 64 0 0 91 0 0 0 0 0 10 0 10 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 10 0 0 0 0 10 55 0 0 10 55 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 19 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _