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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAM19
All Species:
19.39
Human Site:
Y163
Identified Species:
47.41
UniProt:
Q9H013
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H013
NP_150377.1
956
105039
Y163
S
K
G
Q
H
L
I
Y
R
S
E
H
L
K
P
Chimpanzee
Pan troglodytes
XP_001137686
956
105029
Y163
S
K
G
Q
H
L
I
Y
R
S
E
H
L
K
P
Rhesus Macaque
Macaca mulatta
XP_001105246
1098
119747
Y339
S
E
G
Q
H
L
I
Y
R
S
E
H
L
K
P
Dog
Lupus familis
XP_546274
909
99674
Y153
S
E
G
H
H
L
I
Y
R
S
E
H
L
K
L
Cat
Felis silvestris
Mouse
Mus musculus
O35674
920
100842
Y163
S
D
S
Q
H
R
I
Y
R
S
E
H
L
T
L
Rat
Rattus norvegicus
Q9QYV0
816
88034
R95
N
R
D
L
V
P
G
R
P
T
L
V
W
Y
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507222
856
93750
A121
Q
V
H
S
T
S
A
A
M
D
W
L
T
H
F
Chicken
Gallus gallus
XP_414565
899
97545
Y150
S
T
D
Q
H
R
I
Y
R
L
D
D
L
K
M
Frog
Xenopus laevis
O42596
935
104143
K193
F
H
S
V
Y
K
S
K
V
L
E
F
P
L
D
Zebra Danio
Brachydanio rerio
XP_699915
860
93382
T120
V
M
A
K
P
Q
R
T
N
R
E
R
R
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
80.2
83.5
N.A.
79.7
33.4
N.A.
68
57.1
30.1
46.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
81.8
87.8
N.A.
87.3
46.7
N.A.
75.7
69.9
44.6
59.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
66.6
0
N.A.
0
53.3
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
66.6
20
N.A.
0
60
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
10
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
20
0
0
0
0
0
0
10
10
10
0
10
10
% D
% Glu:
0
20
0
0
0
0
0
0
0
0
70
0
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% F
% Gly:
0
0
40
0
0
0
10
0
0
0
0
0
0
0
0
% G
% His:
0
10
10
10
60
0
0
0
0
0
0
50
0
10
0
% H
% Ile:
0
0
0
0
0
0
60
0
0
0
0
0
0
0
0
% I
% Lys:
0
20
0
10
0
10
0
10
0
0
0
0
0
50
0
% K
% Leu:
0
0
0
10
0
40
0
0
0
20
10
10
60
10
20
% L
% Met:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
10
% M
% Asn:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
10
10
0
0
10
0
0
0
10
0
30
% P
% Gln:
10
0
0
50
0
10
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
10
0
0
0
20
10
10
60
10
0
10
10
0
0
% R
% Ser:
60
0
20
10
0
10
10
0
0
50
0
0
0
0
0
% S
% Thr:
0
10
0
0
10
0
0
10
0
10
0
0
10
10
0
% T
% Val:
10
10
0
10
10
0
0
0
10
0
0
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% W
% Tyr:
0
0
0
0
10
0
0
60
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _