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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC22A4
All Species:
23.03
Human Site:
S80
Identified Species:
46.06
UniProt:
Q9H015
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H015
NP_003050.2
551
62155
S80
D
G
R
E
V
P
H
S
C
S
R
Y
R
L
A
Chimpanzee
Pan troglodytes
XP_001163062
551
62237
S80
D
G
R
E
V
P
H
S
C
S
R
Y
R
L
A
Rhesus Macaque
Macaca mulatta
XP_001103789
557
62650
S80
D
G
R
E
V
P
H
S
C
R
R
Y
R
L
A
Dog
Lupus familis
XP_531899
716
79502
S243
D
G
R
E
V
P
H
S
C
R
R
Y
R
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z306
553
62272
S80
D
G
R
Q
V
P
Q
S
C
R
R
Y
R
L
A
Rat
Rattus norvegicus
Q9R141
553
62344
S80
D
G
R
Q
V
P
Q
S
C
R
R
Y
R
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510318
557
62019
R80
G
A
G
R
G
P
S
R
C
R
R
Y
R
L
Q
Chicken
Gallus gallus
NP_001139603
553
61767
R80
G
G
V
T
E
P
S
R
C
R
R
Y
R
L
A
Frog
Xenopus laevis
Q66KG0
566
63736
D77
W
E
S
W
T
S
K
D
Y
L
V
V
Q
Q
E
Zebra Danio
Brachydanio rerio
Q6NYN7
560
61953
E79
L
G
L
N
G
K
L
E
R
C
K
R
Y
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCA2
548
60985
Y79
E
N
E
R
C
S
Y
Y
D
V
D
Y
T
E
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9U539
585
65444
S93
T
N
D
T
Q
I
L
S
C
K
Q
Y
N
E
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
75.9
69.5
N.A.
84.8
85.3
N.A.
68.5
76.4
32.8
29.6
N.A.
36.1
N.A.
28
N.A.
Protein Similarity:
100
99.4
86.3
72.9
N.A.
92
92
N.A.
81.1
86.2
54.2
49.6
N.A.
56.4
N.A.
48.3
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
80
80
N.A.
40
53.3
0
6.6
N.A.
6.6
N.A.
20
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
86.6
86.6
N.A.
40
53.3
6.6
13.3
N.A.
20
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
59
% A
% Cys:
0
0
0
0
9
0
0
0
75
9
0
0
0
0
0
% C
% Asp:
50
0
9
0
0
0
0
9
9
0
9
0
0
0
0
% D
% Glu:
9
9
9
34
9
0
0
9
0
0
0
0
0
17
17
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
17
67
9
0
17
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
34
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
9
9
0
0
9
9
0
0
0
0
% K
% Leu:
9
0
9
0
0
0
17
0
0
9
0
0
0
67
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
17
0
9
0
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
67
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
17
9
0
17
0
0
0
9
0
9
9
9
% Q
% Arg:
0
0
50
17
0
0
0
17
9
50
67
9
67
0
0
% R
% Ser:
0
0
9
0
0
17
17
59
0
17
0
0
0
0
0
% S
% Thr:
9
0
0
17
9
0
0
0
0
0
0
0
9
9
17
% T
% Val:
0
0
9
0
50
0
0
0
0
9
9
9
0
0
0
% V
% Trp:
9
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
9
9
0
0
84
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _