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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM54B
All Species:
4.24
Human Site:
S225
Identified Species:
11.67
UniProt:
Q9H019
Number Species:
8
Phosphosite Substitution
Charge Score:
0.88
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H019
NP_001093095.1
292
31957
S225
H
K
A
A
C
S
S
S
E
E
D
D
C
V
S
Chimpanzee
Pan troglodytes
XP_001135531
289
31664
E224
A
A
C
S
S
S
E
E
D
D
C
V
S
L
S
Rhesus Macaque
Macaca mulatta
XP_001107680
289
31694
E224
A
T
C
S
S
S
E
E
D
D
C
I
S
L
S
Dog
Lupus familis
XP_544491
292
32035
S225
H
K
A
T
C
S
S
S
E
E
D
D
C
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWE0
289
31708
E224
T
T
C
S
S
S
E
E
D
D
C
I
S
L
S
Rat
Rattus norvegicus
Q5XII9
289
31712
E224
T
T
C
S
S
S
E
E
D
D
C
I
S
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417733
286
31421
E222
E
P
K
D
P
D
E
E
D
S
V
S
L
S
K
Frog
Xenopus laevis
Q6GP48
319
35722
D254
N
M
S
D
D
D
E
D
S
M
C
L
S
K
S
Zebra Danio
Brachydanio rerio
Q7T3E8
309
34881
E240
R
P
T
M
D
F
R
E
P
E
E
D
T
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
97.2
98.6
N.A.
94.8
94.8
N.A.
N.A.
78
52.3
54
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.9
97.9
98.9
N.A.
96.5
96.9
N.A.
N.A.
85.2
69.9
66.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
13.3
93.3
N.A.
13.3
13.3
N.A.
N.A.
0
6.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
40
93.3
N.A.
40
40
N.A.
N.A.
6.6
20
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
23
12
23
12
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
45
0
23
0
0
0
0
0
56
0
23
0
0
% C
% Asp:
0
0
0
23
23
23
0
12
56
45
23
34
0
0
0
% D
% Glu:
12
0
0
0
0
0
67
67
23
34
12
0
0
0
0
% E
% Phe:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
23
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
34
0
0
0
% I
% Lys:
0
23
12
0
0
0
0
0
0
0
0
0
0
12
12
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
12
12
45
0
% L
% Met:
0
12
0
12
0
0
0
0
0
12
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
23
0
0
12
0
0
0
12
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
12
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
12
45
45
67
23
23
12
12
0
12
56
12
89
% S
% Thr:
23
34
12
12
0
0
0
0
0
0
0
0
12
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
12
12
0
34
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _