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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM126A
All Species:
26.97
Human Site:
Y178
Identified Species:
65.93
UniProt:
Q9H061
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H061
NP_115649.1
195
21527
Y178
A
Y
L
G
S
E
Q
Y
K
L
L
I
K
A
L
Chimpanzee
Pan troglodytes
XP_001174313
196
21720
Y179
A
F
L
G
F
K
Q
Y
K
L
L
L
K
A
L
Rhesus Macaque
Macaca mulatta
XP_001100286
195
21680
Y178
A
Y
L
G
S
K
Q
Y
K
L
L
I
K
A
L
Dog
Lupus familis
XP_850546
197
21655
Y180
A
Y
L
G
S
R
Q
Y
K
L
I
I
K
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8Y1
196
21521
Y179
S
Y
L
G
S
R
Q
Y
K
L
L
I
K
A
L
Rat
Rattus norvegicus
Q5HZA9
196
21639
Y179
A
Y
L
G
S
R
Q
Y
K
L
L
I
K
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512850
372
40099
Y352
F
Y
L
G
S
R
Q
Y
G
I
F
I
K
A
L
Chicken
Gallus gallus
XP_001235495
209
23236
H188
V
F
L
A
T
K
H
H
G
I
Y
V
K
V
L
Frog
Xenopus laevis
NP_001079826
202
22332
Y181
V
Y
I
S
S
R
H
Y
T
I
Y
E
Q
M
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782908
178
19909
F162
A
F
V
A
D
R
Q
F
R
L
A
H
T
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.9
92.3
79.6
N.A.
70.9
69.9
N.A.
35.4
41.6
48
N.A.
N.A.
N.A.
N.A.
N.A.
31.2
Protein Similarity:
100
84.6
95.9
87.8
N.A.
84.1
81.1
N.A.
43.2
63.1
65.8
N.A.
N.A.
N.A.
N.A.
N.A.
47.6
P-Site Identity:
100
73.3
93.3
86.6
N.A.
86.6
93.3
N.A.
66.6
20
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
93.3
100
93.3
N.A.
93.3
93.3
N.A.
73.3
60
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
60
0
0
20
0
0
0
0
0
0
10
0
0
70
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
10
0
0
0
0
0
10
0
10
0
% E
% Phe:
10
30
0
0
10
0
0
10
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
70
0
0
0
0
20
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
20
10
0
0
0
10
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
30
10
60
0
0
0
% I
% Lys:
0
0
0
0
0
30
0
0
60
0
0
0
80
0
0
% K
% Leu:
0
0
80
0
0
0
0
0
0
70
50
10
0
0
100
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
80
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
0
0
60
0
0
10
0
0
0
0
0
0
% R
% Ser:
10
0
0
10
70
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
10
0
0
0
10
0
0
0
10
0
0
% T
% Val:
20
0
10
0
0
0
0
0
0
0
0
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
70
0
0
0
0
0
80
0
0
20
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _