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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MIS12
All Species:
8.48
Human Site:
T130
Identified Species:
23.33
UniProt:
Q9H081
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H081
NP_076944.1
205
24140
T130
Q
L
Q
E
K
Y
K
T
E
L
C
T
K
Q
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001101579
205
24055
T130
Q
L
Q
E
K
Y
K
T
E
L
C
T
K
Q
A
Dog
Lupus familis
XP_545523
206
24174
T131
Q
L
Q
E
K
Y
K
T
E
L
G
A
K
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9CY25
206
24112
V131
E
L
Q
E
K
Y
K
V
E
L
C
T
E
Q
A
Rat
Rattus norvegicus
Q7TQ72
206
24142
V131
E
L
Q
E
K
Y
K
V
E
L
C
T
E
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521782
371
41132
A131
R
L
R
G
R
Y
E
A
E
V
R
A
G
R
A
Chicken
Gallus gallus
Q1T769
210
24672
A131
Q
L
Q
Q
Q
C
R
A
E
A
A
A
G
Q
A
Frog
Xenopus laevis
NP_001085804
216
25625
A126
N
L
E
K
K
C
K
A
E
T
L
A
T
Q
R
Zebra Danio
Brachydanio rerio
NP_956672
215
24821
A140
K
L
L
Q
A
Y
E
A
E
V
C
S
K
Q
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99
80
N.A.
78.1
80.5
N.A.
29.9
59
47.6
36.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
99
86.8
N.A.
89.3
90.2
N.A.
42.8
73.8
65.7
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
100
86.6
N.A.
80
80
N.A.
26.6
40
33.3
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
86.6
N.A.
93.3
93.3
N.A.
66.6
60
46.6
80
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
0
0
45
0
12
12
45
0
0
89
% A
% Cys:
0
0
0
0
0
23
0
0
0
0
56
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
23
0
12
56
0
0
23
0
100
0
0
0
23
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
12
0
0
0
0
0
0
12
0
23
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
12
0
0
12
67
0
67
0
0
0
0
0
45
0
0
% K
% Leu:
0
100
12
0
0
0
0
0
0
56
12
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
45
0
67
23
12
0
0
0
0
0
0
0
0
89
0
% Q
% Arg:
12
0
12
0
12
0
12
0
0
0
12
0
0
12
12
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
34
0
12
0
45
12
0
0
% T
% Val:
0
0
0
0
0
0
0
23
0
23
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
78
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _