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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUAK2
All Species:
28.48
Human Site:
S106
Identified Species:
52.22
UniProt:
Q9H093
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H093
NP_112214.1
628
69612
S106
R
E
I
E
I
M
S
S
L
N
H
P
H
I
I
Chimpanzee
Pan troglodytes
XP_001161041
661
74289
S109
R
E
I
E
I
M
S
S
L
N
H
P
H
I
I
Rhesus Macaque
Macaca mulatta
XP_001088883
675
74111
S106
R
E
I
E
I
M
S
S
L
N
H
P
H
I
I
Dog
Lupus familis
XP_545687
631
69738
S111
R
E
I
E
I
M
S
S
L
N
H
P
H
I
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BZN4
639
70657
S110
R
E
I
E
I
M
S
S
L
N
H
P
H
I
I
Rat
Rattus norvegicus
Q66HE5
630
69934
S110
R
E
I
E
I
M
S
S
L
N
H
P
H
I
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515855
679
75174
S150
R
E
I
E
I
M
S
S
L
N
H
P
H
I
I
Chicken
Gallus gallus
Q9IA88
798
88848
Q90
P
H
I
I
K
L
Y
Q
V
M
E
T
K
D
M
Frog
Xenopus laevis
NP_001088596
570
64876
P83
I
M
S
S
I
C
H
P
N
I
I
S
V
Y
E
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
M112
R
E
V
Q
I
M
K
M
L
R
H
P
H
I
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
Q223
R
E
V
K
I
M
K
Q
L
D
H
P
N
I
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
T25
P
N
Y
K
L
G
K
T
L
G
I
G
S
F
G
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
L109
R
E
I
S
Y
L
R
L
L
R
H
P
H
I
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.8
82
86.6
N.A.
85.4
85.7
N.A.
68.7
28.8
51.4
22.5
N.A.
N.A.
N.A.
22.1
N.A.
Protein Similarity:
100
65.9
84.5
90.1
N.A.
89.5
90.9
N.A.
75.8
43.4
64
33.4
N.A.
N.A.
N.A.
34.4
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
6.6
6.6
66.6
N.A.
N.A.
N.A.
53.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
26.6
6.6
80
N.A.
N.A.
N.A.
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.4
25.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.5
44.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% D
% Glu:
0
77
0
54
0
0
0
0
0
0
8
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
8
0
0
0
8
0
8
0
0
8
% G
% His:
0
8
0
0
0
0
8
0
0
0
77
0
70
0
0
% H
% Ile:
8
0
70
8
77
0
0
0
0
8
16
0
0
77
70
% I
% Lys:
0
0
0
16
8
0
24
0
0
0
0
0
8
0
0
% K
% Leu:
0
0
0
0
8
16
0
8
85
0
0
0
0
0
0
% L
% Met:
0
8
0
0
0
70
0
8
0
8
0
0
0
0
8
% M
% Asn:
0
8
0
0
0
0
0
0
8
54
0
0
8
0
0
% N
% Pro:
16
0
0
0
0
0
0
8
0
0
0
77
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
16
0
0
0
0
0
0
0
% Q
% Arg:
77
0
0
0
0
0
8
0
0
16
0
0
0
0
0
% R
% Ser:
0
0
8
16
0
0
54
54
0
0
0
8
8
0
0
% S
% Thr:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% T
% Val:
0
0
16
0
0
0
0
0
8
0
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
8
0
8
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _