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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUAK2 All Species: 28.48
Human Site: S106 Identified Species: 52.22
UniProt: Q9H093 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H093 NP_112214.1 628 69612 S106 R E I E I M S S L N H P H I I
Chimpanzee Pan troglodytes XP_001161041 661 74289 S109 R E I E I M S S L N H P H I I
Rhesus Macaque Macaca mulatta XP_001088883 675 74111 S106 R E I E I M S S L N H P H I I
Dog Lupus familis XP_545687 631 69738 S111 R E I E I M S S L N H P H I I
Cat Felis silvestris
Mouse Mus musculus Q8BZN4 639 70657 S110 R E I E I M S S L N H P H I I
Rat Rattus norvegicus Q66HE5 630 69934 S110 R E I E I M S S L N H P H I I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515855 679 75174 S150 R E I E I M S S L N H P H I I
Chicken Gallus gallus Q9IA88 798 88848 Q90 P H I I K L Y Q V M E T K D M
Frog Xenopus laevis NP_001088596 570 64876 P83 I M S S I C H P N I I S V Y E
Zebra Danio Brachydanio rerio Q6NSM8 1187 130949 M112 R E V Q I M K M L R H P H I I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9TW45 1192 126331 Q223 R E V K I M K Q L D H P N I V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P92958 512 58671 T25 P N Y K L G K T L G I G S F G
Baker's Yeast Sacchar. cerevisiae P06782 633 72027 L109 R E I S Y L R L L R H P H I I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 53.8 82 86.6 N.A. 85.4 85.7 N.A. 68.7 28.8 51.4 22.5 N.A. N.A. N.A. 22.1 N.A.
Protein Similarity: 100 65.9 84.5 90.1 N.A. 89.5 90.9 N.A. 75.8 43.4 64 33.4 N.A. N.A. N.A. 34.4 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 6.6 6.6 66.6 N.A. N.A. N.A. 53.3 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 26.6 6.6 80 N.A. N.A. N.A. 86.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 29.4 25.9 N.A.
Protein Similarity: N.A. N.A. N.A. 46.5 44.7 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 60 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 8 0 0 0 8 0 % D
% Glu: 0 77 0 54 0 0 0 0 0 0 8 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % F
% Gly: 0 0 0 0 0 8 0 0 0 8 0 8 0 0 8 % G
% His: 0 8 0 0 0 0 8 0 0 0 77 0 70 0 0 % H
% Ile: 8 0 70 8 77 0 0 0 0 8 16 0 0 77 70 % I
% Lys: 0 0 0 16 8 0 24 0 0 0 0 0 8 0 0 % K
% Leu: 0 0 0 0 8 16 0 8 85 0 0 0 0 0 0 % L
% Met: 0 8 0 0 0 70 0 8 0 8 0 0 0 0 8 % M
% Asn: 0 8 0 0 0 0 0 0 8 54 0 0 8 0 0 % N
% Pro: 16 0 0 0 0 0 0 8 0 0 0 77 0 0 0 % P
% Gln: 0 0 0 8 0 0 0 16 0 0 0 0 0 0 0 % Q
% Arg: 77 0 0 0 0 0 8 0 0 16 0 0 0 0 0 % R
% Ser: 0 0 8 16 0 0 54 54 0 0 0 8 8 0 0 % S
% Thr: 0 0 0 0 0 0 0 8 0 0 0 8 0 0 0 % T
% Val: 0 0 16 0 0 0 0 0 8 0 0 0 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 8 0 8 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _